{"id":"W2046236577","doi":"10.1097/00006676-200004000-00008","title":"Cell Loss in Isolated Human Islets Occurs by Apoptosis","year":2000,"lang":"en","type":"article","venue":"Pancreas","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":232,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"","keywords":"Islet; Apoptosis; TUNEL assay; DNA fragmentation; Biology; Pancreas; Programmed cell death; Internal medicine; Endocrinology; Beta cell; Fragmentation (computing); Immunocytochemistry; Transplantation; Dispase; Andrology; Molecular biology; Collagenase; Cell biology; Enzyme; Insulin; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001203221,0.0001597049,0.0003311914,0.00009029937,0.00005585703,0.00001411526,0.00006512122,0.0001098253,0.007261061],"category_scores_gemma":[0.00003707168,0.0001452405,0.0000727724,0.0002700514,0.00005313365,0.00006068201,0.000009392147,0.0001711121,0.001009643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000442277,"about_ca_system_score_gemma":0.00002992687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004956526,"about_ca_topic_score_gemma":0.000001654861,"domain_scores_codex":[0.9989374,0.00004778185,0.000252958,0.0002614702,0.0001745061,0.0003259363],"domain_scores_gemma":[0.9994227,0.00005587179,0.00003769593,0.0002703073,0.00002819857,0.0001852204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007821514,0.001673541,0.4083327,0.0002193882,0.0001342622,0.00006874808,0.000695252,0.00001416538,0.3574811,0.0001214054,0.2240774,0.006399956],"study_design_scores_gemma":[0.02349938,0.001784829,0.1611851,0.0006902416,0.000630449,0.00008741116,0.000391795,0.001441756,0.4347352,0.0006119992,0.3734128,0.001529089],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8873776,0.0005776779,0.000009105894,0.0002765268,0.00005139091,0.0001784501,0.00001327481,0.0001006251,0.1114153],"genre_scores_gemma":[0.9832436,0.0001145711,0.00007565493,0.001378934,0.0000722072,0.00002377409,0.0001001466,0.00002242158,0.01496873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2471476,"threshold_uncertainty_score":0.9997682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00827091728042682,"score_gpt":0.2415918255189142,"score_spread":0.2333209082384874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}