{"id":"W2046243829","doi":"10.1038/ncb2960","title":"Integrin β3 links therapy resistance and cancer stem cell properties","year":2014,"lang":"en","type":"letter","venue":"Nature Cell Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Integrin; Cell biology; Cancer research; Cancer stem cell; Stem cell; Cancer therapy; Cell; Cancer; Biology; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002091273,0.000513177,0.00120739,0.0004434112,0.00203633,0.002833485,0.001034487,0.02310839,0.005909511],"category_scores_gemma":[0.01395681,0.0006010372,0.0007656442,0.0003762672,0.002854461,0.002296371,0.00128302,0.02170332,0.002403337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003330104,"about_ca_system_score_gemma":0.001546316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001733129,"about_ca_topic_score_gemma":0.002386819,"domain_scores_codex":[0.9985979,0.0004006447,0.0001416409,0.0001770604,0.0004837073,0.0001990739],"domain_scores_gemma":[0.9960787,0.002751285,0.0002675409,0.0001648308,0.0004395155,0.0002981945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000440862,0.0001625008,0.001123363,0.000108161,0.00004541311,0.002806044,0.0001113643,0.0002439657,0.0021037,0.01126362,0.9423395,0.03925154],"study_design_scores_gemma":[0.0006330503,0.000453578,0.002589279,0.0001894287,0.0001382416,0.003892127,0.000338808,0.002081841,0.005316942,0.04539077,0.9388731,0.0001027181],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.001832173,0.002382438,0.0002695216,0.972516,0.01942161,0.00001603009,0.00005683421,0.00003638145,0.00346899],"genre_scores_gemma":[0.04431804,0.006172037,0.0009738043,0.8335903,0.09285355,0.0001486457,0.00008220608,0.00003773627,0.02182378],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02310839,"threshold_uncertainty_score":0.02416176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02721285652388079,"score_gpt":0.296737626625842,"score_spread":0.2695247701019612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}