{"id":"W2046243829","doi":"10.1038/ncb2960","title":"Integrin β3 links therapy resistance and cancer stem cell properties","year":2014,"lang":"en","type":"letter","venue":"Nature Cell Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Integrin; Cell biology; Cancer research; Cancer stem cell; Stem cell; Cancer therapy; Cell; Cancer; Biology; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0002748102,0.0005291589,0.0008922552,0.0002936532,0.00008733371,0.00003476542,0.0004137768,0.007511752,0.0003386456],"category_scores_gemma":[0.00003373092,0.0003411181,0.0001681991,0.0001821305,0.00049906,0.00001820587,0.0001578063,0.01371076,0.00009086268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001558372,"about_ca_system_score_gemma":0.0003167015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006472012,"about_ca_topic_score_gemma":0.00003239983,"domain_scores_codex":[0.997135,0.0004102159,0.0003830439,0.001009572,0.0003568184,0.0007053964],"domain_scores_gemma":[0.9983457,0.0002218712,0.0002017967,0.0007599572,0.000331551,0.0001391453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004172891,0.00003729356,0.0003195106,0.001180342,0.00005985871,0.000217676,0.00009489433,1.184579e-7,0.1625341,0.000006529163,0.8279055,0.007226802],"study_design_scores_gemma":[0.001042423,0.0003279976,0.00005609166,0.0002246289,0.00003761068,0.00001398157,0.00001496482,0.000008266578,0.1070168,0.00002951124,0.8909087,0.0003190391],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03147914,0.2698808,0.00001548152,0.6696697,0.001105955,0.001733565,0.00006984373,0.0001461569,0.02589934],"genre_scores_gemma":[0.06282076,0.02603694,0.0002326744,0.7191915,0.004295864,0.0001966825,0.0003575942,0.0001707832,0.1866972],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2438438,"threshold_uncertainty_score":0.9999041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02721285652388079,"score_gpt":0.296737626625842,"score_spread":0.2695247701019612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}