{"id":"W2046404869","doi":"10.1016/j.cmet.2008.05.003","title":"Pancreatic Islet α Cell Commands Itself: Secrete More Glucagon!","year":2008,"lang":"en","type":"review","venue":"Cell Metabolism","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Glucagon; Endocrinology; Internal medicine; Glucose homeostasis; Autocrine signalling; Biology; Secretion; Insulin; Islet; Receptor; Glutamate receptor; Pancreatic islets; Insulin resistance; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002394225,0.001110726,0.005168839,0.0005104585,0.0002078566,0.00004963356,0.0003866697,0.0007700099,0.001383882],"category_scores_gemma":[0.000166332,0.0008361192,0.001512663,0.0007497349,0.0002086902,0.00009246471,0.0001377226,0.001079305,0.002170267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001089007,"about_ca_system_score_gemma":0.0006683078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003188279,"about_ca_topic_score_gemma":1.74409e-7,"domain_scores_codex":[0.9961833,0.0002952706,0.001170403,0.0008729557,0.0006602788,0.0008177942],"domain_scores_gemma":[0.9966465,0.0004308484,0.0006229198,0.001476597,0.0001674957,0.0006556636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001543731,0.001591246,0.0001108365,0.1515354,0.002460232,0.001008694,0.001505116,0.000002792816,0.0008516826,0.0003086079,0.3446991,0.4957719],"study_design_scores_gemma":[0.001765729,0.0000785442,0.00002673277,0.003530419,0.007197797,0.000214122,0.00005446136,0.00001875272,0.0006634297,0.00001178918,0.9857159,0.0007223115],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005117086,0.9140316,0.00003165879,0.00004219817,0.001264572,0.001292401,0.0001158166,0.0002103085,0.08249971],"genre_scores_gemma":[0.00004036958,0.9554868,0.0008478556,0.0009004497,0.001594173,0.0002409521,0.0009549889,0.0002188629,0.03971556],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6410168,"threshold_uncertainty_score":0.999529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03130997751315871,"score_gpt":0.2909979746055641,"score_spread":0.2596879970924054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}