{"id":"W2046438285","doi":"10.1016/s0014-2999(00)00336-8","title":"Caffeine blockade of the thermal antihyperalgesic effect of acute amitriptyline in a rat model of neuropathic pain","year":2000,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Amitriptyline; Neuropathic pain; Pharmacology; Caffeine; Medicine; Anesthesia; Antagonist; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004009739,0.0001612002,0.0006330793,0.0001588243,0.00002019631,0.00000134414,0.0002400692,0.00003127149,0.0001833258],"category_scores_gemma":[0.00008889784,0.00009460786,0.0002418622,0.0002175789,0.0001128925,0.00003769235,0.00003950046,0.0003594213,0.000002691451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002260786,"about_ca_system_score_gemma":0.00007924199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003202291,"about_ca_topic_score_gemma":2.722565e-7,"domain_scores_codex":[0.9945167,0.004211821,0.0007360185,0.0001153098,0.0002308477,0.0001893506],"domain_scores_gemma":[0.998935,0.000240716,0.0005105791,0.0001462866,0.00009704632,0.00007035724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002194412,0.0004419913,0.004453568,0.00008845711,0.0003128913,0.0009286147,0.0001951099,0.003154641,0.976723,0.000003184928,0.000176044,0.01132808],"study_design_scores_gemma":[0.01289997,0.004931816,0.005555918,0.0002543868,0.001280048,0.0002978701,0.000008469249,0.02022846,0.9543733,0.000009380156,0.00007440615,0.00008597036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981762,0.0004239391,0.0001480115,0.0004586236,0.0001762285,0.0002477834,0.000009008312,0.000003864006,0.0003563602],"genre_scores_gemma":[0.9986901,0.0002902417,0.0002504853,0.0003991688,0.0001188485,8.99494e-7,0.000001044054,0.00002915309,0.0002200047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0223497,"threshold_uncertainty_score":0.3857996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187025221276823,"score_gpt":0.2716346391122061,"score_spread":0.2597643868994379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}