{"id":"W2046458537","doi":"10.1007/s00253-014-5898-x","title":"A dual mechanism involved in membrane and nucleic acid disruption of AvBD103b, a new avian defensin from the king penguin, against Salmonella enteritidis CVCC3377","year":2014,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Chinese Academy of Agricultural Sciences; Institute of Genetics; Institute of Microbiology, Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Salmonella enteritidis; Intracellular; Biology; Bacterial cell structure; Cell membrane; Microbiology; DNA; Membrane permeability; Antibacterial activity; Flow cytometry; Peptidoglycan; Nucleic acid; Biochemistry; Cell; Salmonella; Cell biology; Bacteria; Cell wall; Membrane; Molecular biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002976773,0.0003473312,0.0006666323,0.0001846406,0.0002154785,0.00001685262,0.0002532618,0.001201485,0.00005506857],"category_scores_gemma":[0.00005324975,0.0002712733,0.00007303128,0.0001601829,0.001355061,0.00005062573,0.0003917058,0.0006604917,0.00003527352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002176591,"about_ca_system_score_gemma":0.00003080366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005059842,"about_ca_topic_score_gemma":0.001442571,"domain_scores_codex":[0.9982049,0.0001803144,0.0004740432,0.0006190883,0.00001614315,0.0005054795],"domain_scores_gemma":[0.9991126,0.0002414661,0.0002460929,0.0003513371,0.00002080606,0.00002771352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002798535,0.00006519038,0.0006249271,0.00002047659,0.00009610026,0.000003980195,0.0005214657,5.414618e-7,0.9757811,0.01224042,0.0002353082,0.01013067],"study_design_scores_gemma":[0.002453519,0.0002503183,0.001721987,0.00009760986,0.00007117585,0.0001802189,0.001481502,0.000007926668,0.9846346,0.00408378,0.004652325,0.0003650286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946997,0.001779978,0.0005123235,0.002123447,0.0002298251,0.0003602665,0.00009467113,0.00009317455,0.000106621],"genre_scores_gemma":[0.9969957,0.001116909,0.0006210983,0.0008883188,0.00004739677,0.00001155639,0.0002461082,0.00002619812,0.00004671435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009765643,"threshold_uncertainty_score":0.999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007516967326187376,"score_gpt":0.1871901080159739,"score_spread":0.1796731406897865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}