{"id":"W2046458537","doi":"10.1007/s00253-014-5898-x","title":"A dual mechanism involved in membrane and nucleic acid disruption of AvBD103b, a new avian defensin from the king penguin, against Salmonella enteritidis CVCC3377","year":2014,"lang":"en","type":"article","venue":"Applied Microbiology and Biotechnology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Chinese Academy of Agricultural Sciences; Institute of Genetics; Institute of Microbiology, Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Salmonella enteritidis; Intracellular; Biology; Bacterial cell structure; Cell membrane; Microbiology; DNA; Membrane permeability; Antibacterial activity; Flow cytometry; Peptidoglycan; Nucleic acid; Biochemistry; Cell; Salmonella; Cell biology; Bacteria; Cell wall; Membrane; Molecular biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000740422,0.0002928555,0.0001826992,0.00009136749,0.0001544298,0.0002182044,0.0001541467,0.000373873,0.0006731735],"category_scores_gemma":[0.00006837786,0.00008951795,0.0002075199,0.00004251006,0.0002191888,0.0001892948,0.0001731057,0.0004430066,0.0001870181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002229325,"about_ca_system_score_gemma":0.0001252772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006812789,"about_ca_topic_score_gemma":0.0006148184,"domain_scores_codex":[0.9999163,0.00001058855,0.000004767918,0.0000200116,0.00001782969,0.00003038587],"domain_scores_gemma":[0.9999547,0.000005804989,0.00001530657,0.000004301585,0.000007497155,0.0000124687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004239095,0.000005653722,0.00008486534,0.00001802597,0.000001992684,0.00004096289,0.000006887962,0.00001757982,0.9992377,0.00005816052,0.00001283756,0.0004729686],"study_design_scores_gemma":[0.00002618709,0.0002922129,0.005185666,0.00000770502,0.00001590225,0.0005793551,0.00006410769,0.0008655951,0.9907658,0.00005845333,0.002132567,0.000006335674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994998,0.001110968,0.002586681,0.00008150014,0.00003422413,0.0000190476,0.00008911501,0.00002313987,0.001057362],"genre_scores_gemma":[0.9969624,0.0002162456,0.001281562,0.00004890678,0.00000309949,0.000008283361,0.00009270722,0.000004073045,0.001382754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006812789,"threshold_uncertainty_score":0.002251983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007516967326187376,"score_gpt":0.1871901080159739,"score_spread":0.1796731406897865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}