{"id":"W2046487711","doi":"10.1097/mib.0b013e318281f2b7","title":"52-Week Efficacy of Adalimumab in Patients with Moderately to Severely Active Ulcerative Colitis Who Failed Corticosteroids and/or Immunosuppressants","year":2013,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"UCB Pharma; Genentech; Atlantic Healthcare; Relypsa; Astellas Pharma; Eisai; ActoGeniX; Shire; Bristol-Myers Squibb; Eli Lilly and Company; Orexigen Therapeutics; Biogen; Celgene; Therakos; Novo Nordisk; Teva Pharmaceutical Industries; Gilead Sciences; Takeda Oncology; Tillotts Pharma; Amgen; Pfizer; Ironwood Pharmaceuticals, Incorporated","keywords":"Ulcerative colitis; Adalimumab; Medicine; Gastroenterology; Internal medicine; Tumor necrosis factor alpha; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006101184,0.0004337046,0.0003903186,0.0001503471,0.0001107841,0.00008700592,0.0002862265,0.0001554918,0.0001295182],"category_scores_gemma":[0.0002350095,0.0003694347,0.00009201057,0.0001210496,0.0002530418,0.00008288579,0.0002474306,0.0001217592,0.00003357876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000653949,"about_ca_system_score_gemma":0.0003229429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005134082,"about_ca_topic_score_gemma":0.0002283828,"domain_scores_codex":[0.9976801,0.0002304636,0.0005663921,0.0006432332,0.000369869,0.0005099251],"domain_scores_gemma":[0.9982363,0.00005983412,0.0002346424,0.0005856633,0.0004384239,0.0004451225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1398821,0.001769881,0.8473468,0.0003799006,0.0005545214,0.000285499,0.00131656,0.001327495,0.001478655,0.00005605083,0.001274054,0.004328505],"study_design_scores_gemma":[0.005723851,0.0006992886,0.989331,0.0001892777,0.0000630635,0.000001605336,0.0002365281,0.00009126047,0.003053272,0.00003817462,0.00007139971,0.0005012735],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971818,0.00005023342,0.00002168547,0.00002519446,0.0000642603,0.001936857,0.0005230876,0.00004117603,0.0001556801],"genre_scores_gemma":[0.9988366,0.00001910255,0.00007886121,0.0002188003,0.00005079882,0.0004099784,0.0001653708,0.00008361829,0.0001368825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1419842,"threshold_uncertainty_score":0.9998758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006517874569077723,"score_gpt":0.2184965100514673,"score_spread":0.2119786354823895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}