{"id":"W2046576482","doi":"10.1503/cmaj.130989","title":"New treatments for metastatic melanoma","year":2014,"lang":"en","type":"review","venue":"Canadian Medical Association Journal","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Dacarbazine; Medicine; Metastatic melanoma; Melanoma; Randomized controlled trial; Chemotherapy; Overall survival; Standard of care; Surgery; Oncology; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004887569,0.000820769,0.0009544974,0.001958638,0.0003204302,0.0006010595,0.0008878807,0.0009701212,0.006841869],"category_scores_gemma":[0.0007115019,0.0002159078,0.0006372146,0.0009590773,0.000463931,0.001208145,0.0006677725,0.002925453,0.002521936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006349622,"about_ca_system_score_gemma":0.0007237369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001586565,"about_ca_topic_score_gemma":0.005959473,"domain_scores_codex":[0.9997492,0.00004189967,0.00002441586,0.00004569718,0.0001146987,0.00002411151],"domain_scores_gemma":[0.9997925,0.0000820784,0.00003405533,0.000007765148,0.00005536072,0.00002830692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008893856,0.00007693152,0.0001129679,0.01006308,0.00007080576,0.0001767478,0.00003574204,0.0002214203,0.001299553,0.003400722,0.05621069,0.9282424],"study_design_scores_gemma":[0.00005610557,0.0001263255,0.0006325589,0.003636276,0.00008286379,0.001307674,0.00002952907,0.00005483835,0.0002542747,0.001974412,0.9918295,0.00001566655],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009122476,0.9970803,0.0001241234,0.0006388976,0.0004765794,0.000008882057,0.00003186179,0.000008694725,0.001539392],"genre_scores_gemma":[0.0008687676,0.9961663,0.0002089704,0.0009162032,0.0004490434,0.00001181625,0.00005336407,0.000002567891,0.001322843],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006841869,"threshold_uncertainty_score":0.0228883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01976847048566492,"score_gpt":0.2934463058635469,"score_spread":0.2736778353778819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}