{"id":"W2046628605","doi":"10.1002/art.20217","title":"Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti–tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: A randomized, placebo‐controlled, 52‐week trial","year":2004,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1171,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"","keywords":"Adalimumab; Medicine; Rheumatoid arthritis; Concomitant; Internal medicine; Placebo; Rheumatology; Methotrexate; Infliximab; Gastroenterology; Randomized controlled trial; Synovitis; Surgery; Tumor necrosis factor alpha; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024273,0.001906923,0.003318044,0.0004759975,0.0006191511,0.001362647,0.00106403,0.002832465,0.004372953],"category_scores_gemma":[0.00197383,0.0009310933,0.002210394,0.0004224891,0.001369,0.0009807308,0.0004155922,0.002733178,0.0008156687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006170324,"about_ca_system_score_gemma":0.0007676577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000749204,"about_ca_topic_score_gemma":0.001216933,"domain_scores_codex":[0.9989281,0.0005733965,0.00008981083,0.0001947698,0.00009458471,0.0001193051],"domain_scores_gemma":[0.9985814,0.0004228424,0.0003845696,0.0001176298,0.0001033733,0.0003901763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9838356,0.004512875,0.0008827614,0.0003937823,0.0007620903,0.00002557143,0.00003206889,0.0001616525,0.001608349,0.00002670523,0.0002382452,0.007520389],"study_design_scores_gemma":[0.9495834,0.04610206,0.003050709,0.00002430637,0.0004238916,0.00003004884,0.00001328723,0.0002606719,0.0002527442,0.00003276683,0.0002161912,0.000009950601],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905037,0.005813754,0.0002654924,0.0004141138,0.0003642474,0.00110441,0.0004117775,0.00006465941,0.001057686],"genre_scores_gemma":[0.9919776,0.002406949,0.0007027582,0.0006329941,0.0006678122,0.001568498,0.0006020094,0.00001216056,0.001429262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004372953,"threshold_uncertainty_score":0.01462901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02185641912536996,"score_gpt":0.2936024261355272,"score_spread":0.2717460070101573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}