{"id":"W2046631216","doi":"10.1038/nrurol.2010.231","title":"Blockade of testicular and adrenal androgens in prostate cancer treatment","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"Wilfrid Laurier University; Université Laval","funders":"","keywords":"Antiandrogens; Antiandrogen; Medicine; Prostate cancer; Androgen; Testosterone (patch); Blockade; Bicalutamide; Internal medicine; Endocrinology; Flutamide; Androgen receptor; Prostate; Abiraterone acetate; Dihydrotestosterone; Dehydroepiandrosterone; Cancer; Hormone; Androgen deprivation therapy; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007426593,0.001060956,0.002309797,0.001912388,0.0002609029,0.0009263646,0.001163801,0.001107413,0.005097593],"category_scores_gemma":[0.0008787995,0.0003819018,0.0007378805,0.002080842,0.0005164608,0.001156197,0.0006419775,0.002421567,0.002520773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006327427,"about_ca_system_score_gemma":0.001210927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001645388,"about_ca_topic_score_gemma":0.004157993,"domain_scores_codex":[0.9997573,0.00004060077,0.00003741403,0.00003456202,0.0001052891,0.00002487173],"domain_scores_gemma":[0.9996544,0.0001749407,0.00006521508,0.000009265957,0.000065139,0.00003104082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002023816,0.0001129414,0.0001402414,0.01626593,0.0001711159,0.000151211,0.00002208213,0.0005438048,0.001443144,0.00145299,0.03251133,0.9469827],"study_design_scores_gemma":[0.0001429487,0.0002956963,0.00108695,0.004182327,0.0004399352,0.001193537,0.00003795876,0.0001536657,0.0006198843,0.001244739,0.9905711,0.0000312579],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007812707,0.9988787,0.00008446238,0.000171931,0.0001675232,0.00000516299,0.00001704776,0.000006852256,0.0005903638],"genre_scores_gemma":[0.0005915529,0.9984363,0.0001345076,0.0002026753,0.0001616513,0.000005852893,0.00002426861,0.000001382488,0.0004419546],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005097593,"threshold_uncertainty_score":0.01705319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06673028031812712,"score_gpt":0.4099033334963851,"score_spread":0.343173053178258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}