{"id":"W2046646964","doi":"10.3727/096368911x601000","title":"Inhibiting Matrix Metalloproteinase by Cell-Based <i>Timp-3</i> Gene Transfer Effectively Treats Acute and Chronic Ischemic Cardiomyopathy","year":2011,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Colorado State University","keywords":"Medicine; Matrix metalloproteinase; Cardiology; Ischemic cardiomyopathy; Internal medicine; Cardiac function curve; Myocardial infarction; Genetic enhancement; Heart failure; Ligation; Extracellular matrix; Gene expression; Ventricular remodeling; Ejection fraction; Biology; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001559076,0.0004173168,0.000383024,0.0001754529,0.0001513925,0.0003093182,0.0002031959,0.0002978057,0.0009994064],"category_scores_gemma":[0.00009483654,0.0001060131,0.0003958247,0.0001358897,0.0002850996,0.0001640277,0.0001057733,0.0008401597,0.0003228511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002249148,"about_ca_system_score_gemma":0.00025371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005132383,"about_ca_topic_score_gemma":0.0008226548,"domain_scores_codex":[0.9998823,0.00001512395,0.00001184087,0.00001785827,0.00002932986,0.000043509],"domain_scores_gemma":[0.999925,0.00001036493,0.00002915436,0.000007233587,0.000008511016,0.00001972995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002172423,0.0001494877,0.0000962093,0.00003713198,0.000006423995,0.00003556791,0.00001154158,0.00004954301,0.9975176,0.00006578967,0.00006995317,0.001743594],"study_design_scores_gemma":[0.00009329159,0.00184921,0.00168928,0.000008743569,0.00004071428,0.0002593935,0.00001982145,0.0006881942,0.9935302,0.0000335631,0.001782879,0.00000458109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925113,0.001406268,0.004152146,0.0001938984,0.00009929352,0.00005701414,0.0002245142,0.000153938,0.001201697],"genre_scores_gemma":[0.9914303,0.001627252,0.004315743,0.00009042049,0.00004560359,0.0000819073,0.0004045625,0.00003144831,0.00197267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009994064,"threshold_uncertainty_score":0.003343403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009447962642628037,"score_gpt":0.2211396571653397,"score_spread":0.2116916945227116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}