{"id":"W2046663210","doi":"10.1016/j.tox.2012.01.004","title":"An ex vivo approach to the differential parenchymal responses induced by cigarette whole smoke and its vapor phase","year":2012,"lang":"en","type":"article","venue":"Toxicology","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; British American Tobacco (Canada)","funders":"China Scholarship Council; British American Tobacco","keywords":"Smoke; Particulates; Cigarette smoke; Chemistry; Gene expression; CYP1B1; Ex vivo; Inhalation exposure; Inhalation; In vivo; Alveolar macrophage; Smoke inhalation; Lung; Parenchyma; Toxicity; Gene; Cytochrome P450; Biology; Toxicology; Pathology; In vitro; Internal medicine; Medicine; Biochemistry; Macrophage; Anatomy; Genetics; Metabolism; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003762568,0.0005717021,0.0002635253,0.0003039414,0.0003358771,0.0003376656,0.0003014921,0.0004572015,0.002671078],"category_scores_gemma":[0.0001231556,0.0002321211,0.0004981257,0.0001865371,0.000537544,0.0004789143,0.0002828448,0.001244254,0.0004041608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001783266,"about_ca_system_score_gemma":0.0002881951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000533848,"about_ca_topic_score_gemma":0.001094234,"domain_scores_codex":[0.9998354,0.00003951302,0.000007107484,0.00004436124,0.00002803346,0.00004556768],"domain_scores_gemma":[0.9998749,0.00005711792,0.00001382246,0.00002079109,0.00001375179,0.00001955125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001232576,0.00004412916,0.00004016849,0.00001659708,0.000002170244,0.00003404279,0.00001251305,0.00001546064,0.9991261,0.00007677978,0.0000105262,0.0004981479],"study_design_scores_gemma":[0.000008884643,0.0006360011,0.000927972,0.000002508252,0.00001171882,0.0001458146,0.00004455886,0.0003237007,0.9972869,0.00004705425,0.0005625167,0.000002281972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9455913,0.003534869,0.04464376,0.0004014903,0.0003102186,0.0001970725,0.0004997926,0.0001583691,0.004663084],"genre_scores_gemma":[0.9686932,0.002522706,0.01787476,0.0002891263,0.0001201734,0.0001679761,0.0005397155,0.00005806848,0.009734229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002671078,"threshold_uncertainty_score":0.00893569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06737115055572891,"score_gpt":0.3445243507721197,"score_spread":0.2771532002163908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}