{"id":"W2046692714","doi":"10.1002/dev.20424","title":"How the epigenome contributes to the development of psychiatric disorders","year":2010,"lang":"en","type":"review","venue":"Developmental Psychobiology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Epigenome; Epigenetics; DNA methylation; Neuroscience; Epigenesis; Psychological repression; Biology; Psychology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004770442,0.0007421881,0.001012106,0.00134291,0.0002325994,0.00064586,0.0006790393,0.001131982,0.002325465],"category_scores_gemma":[0.0005269256,0.0001969034,0.0002738924,0.001366012,0.0005340223,0.0009094761,0.0006126419,0.001240195,0.001527262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006185622,"about_ca_system_score_gemma":0.000830557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001247956,"about_ca_topic_score_gemma":0.002217599,"domain_scores_codex":[0.9998674,0.00003052513,0.0000174647,0.00002816984,0.00004336783,0.00001294547],"domain_scores_gemma":[0.9998063,0.00008014751,0.00002972633,0.000007077821,0.00004974801,0.00002703131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006416285,0.00003638491,0.0005155588,0.005627132,0.00009155308,0.000427465,0.00006815512,0.000345509,0.00302545,0.003990646,0.02020324,0.9656047],"study_design_scores_gemma":[0.00001834784,0.00007310636,0.004108613,0.002256854,0.0001371606,0.004676042,0.0001002264,0.0001551143,0.001543626,0.004324353,0.9825808,0.00002565592],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002312913,0.9977361,0.0002814197,0.000438705,0.0001696115,0.000003722971,0.00001535671,0.000009492036,0.001114373],"genre_scores_gemma":[0.0009097986,0.9979467,0.0002348161,0.0001728482,0.0001777582,0.000003702026,0.00001661633,0.000001230322,0.0005365944],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002325465,"threshold_uncertainty_score":0.007779479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02456534605924897,"score_gpt":0.3039481701675692,"score_spread":0.2793828241083202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}