{"id":"W2046705671","doi":"10.1111/sji.12173","title":"The Activation and Inactivation of Mature <scp>CD</scp>4 <scp>T</scp> cells: A Case for Peripheral Self–Nonself Discrimination","year":2014,"lang":"en","type":"review","venue":"Scandinavian Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antigen; T lymphocyte; Antigen-presenting cell; Cell biology; Biology; Cytotoxic T cell; Immunology; T cell; Immune system; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001347325,0.0008027606,0.002535881,0.0007361976,0.0008408712,0.00008656613,0.0007965301,0.001885805,0.00001607136],"category_scores_gemma":[0.001360348,0.0005508417,0.0008211481,0.0004257944,0.0008967661,0.0003327283,0.0001971582,0.001912481,0.00001944877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003602451,"about_ca_system_score_gemma":0.00042564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004360148,"about_ca_topic_score_gemma":0.00001964441,"domain_scores_codex":[0.9948645,0.001602998,0.002012852,0.000547944,0.0001143395,0.0008573995],"domain_scores_gemma":[0.9890562,0.005206895,0.004381602,0.0006087939,0.000684635,0.00006186214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003665448,0.000994594,0.00004855292,0.008445128,0.008885217,0.0002152409,0.007703758,0.000004032911,0.2907963,0.003901502,0.01805173,0.6605874],"study_design_scores_gemma":[0.002568137,0.002207069,0.00006232053,0.002943397,0.001773351,0.01368645,0.004189091,0.00000261792,0.01568534,0.0005095795,0.9561997,0.0001729426],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04753637,0.946897,0.0008290532,0.0001030558,0.003042635,0.001204332,0.00009526565,0.00004630498,0.0002459608],"genre_scores_gemma":[0.05260289,0.9429864,0.0003466391,0.0000357455,0.0002722338,0.0001257495,0.0002411462,0.0001192945,0.003269853],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.938148,"threshold_uncertainty_score":0.9996943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01598339617669942,"score_gpt":0.2648081254405625,"score_spread":0.2488247292638631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}