{"id":"W2046705671","doi":"10.1111/sji.12173","title":"The Activation and Inactivation of Mature <scp>CD</scp>4 <scp>T</scp> cells: A Case for Peripheral Self–Nonself Discrimination","year":2014,"lang":"en","type":"review","venue":"Scandinavian Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antigen; T lymphocyte; Antigen-presenting cell; Cell biology; Biology; Cytotoxic T cell; Immunology; T cell; Immune system; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005575024,0.0001815226,0.0002127104,0.0002083601,0.000359607,0.001087397,0.0006007499,0.001486027,0.001559611],"category_scores_gemma":[0.0005442379,0.0001295415,0.0002873841,0.0001287456,0.001940284,0.00131163,0.0008356303,0.001758161,0.0005209165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306271,"about_ca_system_score_gemma":0.0002529281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001318221,"about_ca_topic_score_gemma":0.0001094198,"domain_scores_codex":[0.9997483,0.00005733667,0.00001507929,0.00004800148,0.00005391071,0.00007742315],"domain_scores_gemma":[0.9998066,0.00006508483,0.00004102891,0.00003233269,0.00002495267,0.00003013899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008873413,0.0001969409,0.008399084,0.0005664018,0.00004394766,0.008463438,0.002841476,0.00182788,0.4903053,0.3651411,0.01440726,0.1069199],"study_design_scores_gemma":[0.0002103378,0.002119948,0.01467201,0.0003177506,0.00009642944,0.03792462,0.002543864,0.01781357,0.353615,0.3220142,0.2485538,0.0001184207],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7345898,0.01996414,0.138023,0.03808636,0.002474767,0.0002135311,0.00007964896,0.0004861366,0.06608269],"genre_scores_gemma":[0.9590275,0.00388818,0.01793391,0.00503292,0.0009632929,0.0002052356,0.00003592514,0.00004358718,0.01286941],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001559611,"threshold_uncertainty_score":0.005217433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01598339617669942,"score_gpt":0.2648081254405625,"score_spread":0.2488247292638631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}