{"id":"W2046705884","doi":"10.1074/jbc.c800147200","title":"The Rtt106 Histone Chaperone Is Functionally Linked to Transcription Elongation and Is Involved in the Regulation of Spurious Transcription from Cryptic Promoters in Yeast*♦","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Québec","funders":"","keywords":"Promoter; Transcription (linguistics); Chaperone (clinical); Biology; Histone; Yeast; Cell biology; Spurious relationship; RNA polymerase II; Genetics; Transcription factor; Computational biology; Gene; Gene expression; Computer science; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000922519,0.0004434858,0.0003194459,0.0001871394,0.0002443404,0.0003508603,0.0001921148,0.0003021539,0.0007616379],"category_scores_gemma":[0.0001171149,0.0001263111,0.0004444334,0.0002003307,0.0001889338,0.0001718927,0.0002271672,0.000310585,0.0005204657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003577689,"about_ca_system_score_gemma":0.0001405972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004559837,"about_ca_topic_score_gemma":0.0004806185,"domain_scores_codex":[0.9999059,0.000008605004,0.000009035734,0.00003062229,0.00002799534,0.00001773892],"domain_scores_gemma":[0.9997987,0.00001608236,0.00007625763,0.00002649945,0.00002454916,0.00005785749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006718707,0.000009637829,0.0004031263,0.00002482714,0.000004272672,0.0001552753,0.000004940958,0.00007052186,0.9980847,0.00004865667,0.00003999061,0.001086875],"study_design_scores_gemma":[0.00001891058,0.0001254972,0.02265357,0.00001056279,0.00002260644,0.001563567,0.00001757369,0.002137763,0.9694742,0.0001135016,0.00385051,0.00001163054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896787,0.002605409,0.005917595,0.0001272411,0.00005418318,0.0000148463,0.000652851,0.0002503656,0.0006987689],"genre_scores_gemma":[0.9928368,0.0005627554,0.00321956,0.00005156425,0.00001852472,0.0000135906,0.001603816,0.00005653884,0.001636849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007616379,"threshold_uncertainty_score":0.002595782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01761073102269211,"score_gpt":0.2231037042334162,"score_spread":0.2054929732107241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}