{"id":"W2046705884","doi":"10.1074/jbc.c800147200","title":"The Rtt106 Histone Chaperone Is Functionally Linked to Transcription Elongation and Is Involved in the Regulation of Spurious Transcription from Cryptic Promoters in Yeast*♦","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Québec","funders":"","keywords":"Promoter; Transcription (linguistics); Chaperone (clinical); Biology; Histone; Yeast; Cell biology; Spurious relationship; RNA polymerase II; Genetics; Transcription factor; Computational biology; Gene; Gene expression; Computer science; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003178489,0.0001029142,0.0001514513,0.00002311902,0.00005729141,0.00001111215,0.0001509019,0.0001810861,0.00001555295],"category_scores_gemma":[0.00005114935,0.00006525722,0.00007742771,0.00008401142,0.0001041352,0.000006904932,0.00001317205,0.0001552159,4.007034e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004176002,"about_ca_system_score_gemma":0.000040951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001570438,"about_ca_topic_score_gemma":0.00001903154,"domain_scores_codex":[0.9990996,0.00005476327,0.000436713,0.0001544361,0.0001438334,0.0001106971],"domain_scores_gemma":[0.9995337,0.0000217854,0.0002037826,0.0001239207,0.0000789443,0.00003786497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000269362,0.00008382492,0.003533236,0.00001090861,0.00001567417,0.000001679661,0.00063677,0.00006702598,0.9946322,0.000003984692,0.0000777551,0.0006675996],"study_design_scores_gemma":[0.001597125,0.0005657771,0.7555737,0.00006269151,0.00002373486,0.000065648,0.0006547233,0.0007422796,0.238286,0.001329001,0.0009203426,0.0001790377],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973508,0.0007295537,0.0003250832,0.001379951,0.00004687692,0.0001264159,0.00001386868,0.000001378715,0.00002613845],"genre_scores_gemma":[0.9984354,0.0007325562,0.0004071717,0.0002323714,0.0001005925,0.000005988936,0.00004560113,0.00000527595,0.00003503885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7563462,"threshold_uncertainty_score":0.2661112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01761073102269211,"score_gpt":0.2231037042334162,"score_spread":0.2054929732107241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}