{"id":"W2046738633","doi":"10.1002/btpr.1675","title":"A dynamic metabolic flux balance based model of fed‐batch fermentation of <i>bordetella pertussis</i>","year":2012,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada); University of Waterloo","funders":"","keywords":"Bordetella pertussis; Bioreactor; Fermentation; Calibration; Flux balance analysis; Flux (metallurgy); Biomass (ecology); Metabolic flux analysis; Biological system; Maximization; Chemistry; Environmental science; Biochemistry; Biology; Metabolism; Mathematics; Statistics; Botany; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001697193,0.0001470975,0.0002240454,0.0001045633,0.00002828849,0.000002947462,0.000180827,0.0003552807,0.000004567801],"category_scores_gemma":[0.00004143292,0.000135058,0.00007665801,0.0001896267,0.0002156455,0.000005488136,0.00005945794,0.00008616602,0.000001872373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006614753,"about_ca_system_score_gemma":0.00003604766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004478607,"about_ca_topic_score_gemma":0.000002019343,"domain_scores_codex":[0.9991567,0.00002601112,0.0002444257,0.0002340859,0.00008783994,0.0002509783],"domain_scores_gemma":[0.9993471,0.000001301066,0.0001580234,0.0003833888,0.00007431494,0.00003589774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005485263,0.0001482654,0.001486141,0.00005961683,0.00004727906,6.829044e-8,0.00001978611,0.0002831096,0.9889462,0.0002244996,0.00006504839,0.008665162],"study_design_scores_gemma":[0.0003454595,0.0001123739,0.0009873639,0.00001528312,0.00004967785,0.000005247814,0.00001916049,0.004597177,0.9909318,0.00001024157,0.002792337,0.0001338952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835664,0.007630597,0.00800309,0.0003035324,0.000198302,0.0001972509,0.00003607285,0.00004238205,0.00002235451],"genre_scores_gemma":[0.9847859,0.0003452236,0.0145459,0.00002808363,0.00004818056,0.00002522976,0.00008051661,0.00001927407,0.0001216907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008531267,"threshold_uncertainty_score":0.5507504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006944736958407928,"score_gpt":0.2385957207865623,"score_spread":0.2316509838281544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}