{"id":"W2046846306","doi":"10.1371/journal.pone.0010998","title":"Identification of Five Developmental Processes during Chondrogenic Differentiation of Embryonic Stem Cells","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale","keywords":"Chondrogenesis; Cell biology; Embryonic stem cell; Cellular differentiation; Cartilage; Stem cell; Extracellular matrix; Biology; Anatomy; Chemistry; Mesenchymal stem cell; Chondrocyte; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003473875,0.0004044936,0.0002003211,0.0009317948,0.0002710791,0.000588602,0.0002224312,0.0003622838,0.0007031424],"category_scores_gemma":[0.000299344,0.0001675097,0.0003567653,0.0004148344,0.0003341887,0.0004296706,0.0004109958,0.0004035317,0.0003911941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005251427,"about_ca_system_score_gemma":0.0006452146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000854668,"about_ca_topic_score_gemma":0.0009990785,"domain_scores_codex":[0.9997898,0.00002436612,0.00003391083,0.00004129973,0.00008293979,0.00002766789],"domain_scores_gemma":[0.9996137,0.00006301994,0.00009438714,0.00003085668,0.0001449252,0.00005323032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003012134,0.00003677911,0.009226586,0.0003337724,0.00001118034,0.0003187896,0.0001792554,0.0002106263,0.9741172,0.001764668,0.0000801779,0.01341975],"study_design_scores_gemma":[0.000009748378,0.0001862591,0.05189821,0.00006159191,0.00005879434,0.0007684937,0.0001794044,0.001023183,0.9370417,0.0004703985,0.008286498,0.00001577257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9396728,0.01448765,0.03589251,0.0001481508,0.00004886911,0.0001867932,0.001141182,0.0001827409,0.008239293],"genre_scores_gemma":[0.9719461,0.004655737,0.01888424,0.00007192109,0.00001278667,0.0001048753,0.001486944,0.00002390909,0.002813549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009317948,"threshold_uncertainty_score":0.003810227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01733836555722796,"score_gpt":0.2121948873726452,"score_spread":0.1948565218154172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}