{"id":"W2046847329","doi":"10.1016/j.bbagen.2003.08.004","title":"Suppression of apolipoprotein AI gene expression in HepG2 cells by TNF α and IL-1β","year":2003,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Tumor necrosis factor alpha; Endocrinology; Apolipoprotein B; Internal medicine; Messenger RNA; Insulin resistance; Gene expression; Cytokine; Secretion; Alpha (finance); Chemistry; Interleukin 6; Gene; Insulin; Medicine; Cholesterol; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002061605,0.0005772914,0.0003684203,0.0003793381,0.0002715613,0.00049713,0.0001391926,0.000227588,0.002589784],"category_scores_gemma":[0.0001578846,0.0002078288,0.0004860348,0.0004078701,0.0004270571,0.000205157,0.0001728209,0.0008752496,0.001155432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003185181,"about_ca_system_score_gemma":0.0003762654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002565638,"about_ca_topic_score_gemma":0.001845579,"domain_scores_codex":[0.9997799,0.00004870799,0.00003212697,0.00003058802,0.0000405062,0.00006818269],"domain_scores_gemma":[0.9997717,0.00007275719,0.00002640902,0.00005707565,0.00002403805,0.00004794614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000862452,0.00008331527,0.0002147648,0.00004847378,0.000007169957,0.0001326167,0.00005382486,0.00004747772,0.9976346,0.0001140093,0.00009291937,0.0007083155],"study_design_scores_gemma":[0.00006984492,0.0005525431,0.002876022,0.000006346193,0.00001780387,0.0002000443,0.0001310574,0.0004425921,0.9937159,0.00004748171,0.001934281,0.000006028642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904938,0.001514569,0.002268599,0.0003206715,0.0002769995,0.00004866589,0.001221135,0.0002133244,0.003642195],"genre_scores_gemma":[0.9843727,0.001320135,0.001476193,0.0001164443,0.00005669761,0.00009776207,0.001718281,0.00004331109,0.01079847],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002589784,"threshold_uncertainty_score":0.008663714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005907755326557206,"score_gpt":0.2302621991281027,"score_spread":0.2243544438015455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}