{"id":"W2046865337","doi":"10.1021/bc900066j","title":"Radiolabeling of Biodegradable Polymeric Microspheres with [<sup>99m</sup>Tc(CO)<sub>3</sub>]<sup>+</sup> and <i>in Vivo</i> Biodistribution Evaluation using MicroSPECT/CT Imaging","year":2009,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biodistribution; Chemistry; In vivo; Microparticle; Microsphere; Ligand (biochemistry); Spleen; Radiochemistry; Nuclear chemistry; In vitro; Chemical engineering; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000381492,0.0004418072,0.0005632273,0.00005305736,0.0001961089,0.00007140076,0.0001643686,0.0001248406,0.00009498082],"category_scores_gemma":[0.00007059508,0.0004218848,0.0001184584,0.0006121764,0.0003375174,0.0001717974,0.00003168806,0.0003864336,0.000004562803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004007979,"about_ca_system_score_gemma":0.0002696406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004807556,"about_ca_topic_score_gemma":3.816978e-7,"domain_scores_codex":[0.9975534,0.00003747967,0.000665847,0.0007600611,0.0004018363,0.000581379],"domain_scores_gemma":[0.9987082,0.00005956007,0.0002599404,0.0004879645,0.0001921411,0.0002921823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002778035,0.0002538381,0.005264461,0.0003605735,0.00005257068,0.00003479193,0.00006361942,0.0006838909,0.9907472,0.000003067585,0.0002140574,0.00204412],"study_design_scores_gemma":[0.003062921,0.00004110474,0.0002942834,0.0004304311,0.0002940571,0.0006710846,0.0002845806,0.04051294,0.9535191,0.0000431008,0.0004332331,0.0004131306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920599,0.005765391,0.0002062685,0.0005704706,0.000009079369,0.0006123507,0.0001944004,0.00008386953,0.0004982073],"genre_scores_gemma":[0.9979997,0.000321676,0.0009233982,0.0002064375,0.0001531676,0.00003602522,0.0002771879,0.00003598341,0.0000464033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03982905,"threshold_uncertainty_score":0.9998233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704004641775867,"score_gpt":0.2841814738189349,"score_spread":0.2671414274011762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}