{"id":"W2046897800","doi":"10.1097/mib.0000000000000343","title":"Harnessing Regulatory T Cells for the Treatment of Inflammatory Bowel Disease","year":2015,"lang":"en","type":"review","venue":"Inflammatory Bowel Diseases","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"FOXP3; Immunology; Inflammatory bowel disease; Immune system; Inflammation; Lamina propria; Immune tolerance; Regulatory T cell; Antigen; Biology; Medicine; Disease; T cell; IL-2 receptor; Pathology; Epithelium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002767805,0.0008699346,0.001414316,0.0003176191,0.0004582142,0.00006710736,0.0005439827,0.000520107,0.0005536367],"category_scores_gemma":[0.0001216864,0.0005811025,0.001751698,0.0001156215,0.0005715955,0.000260518,0.00008638749,0.0002820236,0.0006382613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004841945,"about_ca_system_score_gemma":0.001427472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009430369,"about_ca_topic_score_gemma":0.000003231875,"domain_scores_codex":[0.9967484,0.0005224082,0.001356668,0.0006665111,0.0001460391,0.0005600143],"domain_scores_gemma":[0.9961981,0.0007716077,0.001214449,0.001327035,0.0003238801,0.000164916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001957458,0.001542654,0.000425106,0.02328249,0.003980931,0.00006214844,0.000510953,0.000093471,0.000282477,0.0005254843,0.1178953,0.8494415],"study_design_scores_gemma":[0.001204337,0.0001841071,0.0006736531,0.002699704,0.004008694,0.00001134577,0.0001333725,0.0000115878,0.0001457642,0.00003194528,0.9903244,0.0005711298],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004615692,0.9878535,0.00003121051,0.00002017629,0.008326748,0.002518315,0.0004760352,0.0001809836,0.0001314176],"genre_scores_gemma":[0.0002765644,0.9827815,0.000005906457,0.00004666566,0.0004367662,0.001342742,0.001177668,0.0001453148,0.01378688],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8724291,"threshold_uncertainty_score":0.9996641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02809692742349058,"score_gpt":0.2831079316843845,"score_spread":0.255011004260894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}