{"id":"W2046908575","doi":"10.1002/em.1017","title":"Evaluation of the rodent micronucleus assay by a 28‐day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)–Mammalian Mutagenicity Study Group (MMS)","year":2001,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Micronucleus test; Micronucleus; Genotoxicity; Mutagen; Dose; Toxicology; Pharmacology; Biology; Clastogen; Toxicity; Bone marrow; Carcinogen; Medicine; Immunology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001880689,0.000553217,0.0004942456,0.00002225194,0.0006865223,0.0000485561,0.0006781001,0.0001423907,0.00003649495],"category_scores_gemma":[0.00003100399,0.0003098345,0.0004089243,0.0002577837,0.0006668051,0.00001748207,0.0006819282,0.0001328403,7.48182e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003228587,"about_ca_system_score_gemma":0.0001137514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004340732,"about_ca_topic_score_gemma":0.0008818909,"domain_scores_codex":[0.995311,0.001646426,0.0007279918,0.000830429,0.001103524,0.0003805835],"domain_scores_gemma":[0.9979254,0.0001191228,0.0006727671,0.001129525,0.00006797734,0.00008519165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002610176,0.009920373,0.1225282,0.00001386318,0.001572147,0.000001349114,0.004774156,0.0001728386,0.8579982,5.200262e-7,0.0003623634,0.002394969],"study_design_scores_gemma":[0.007531315,0.007595464,0.2961647,0.00001187622,0.002263571,0.000007940022,0.08998029,0.000229359,0.5920296,0.000003986417,0.003756161,0.0004257286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9359962,0.001408525,0.00008157187,0.000139915,0.00006362744,0.06060535,0.001682838,0.000004641289,0.00001735681],"genre_scores_gemma":[0.9835045,0.0001543805,0.00004522653,0.0001116086,0.00003805944,0.01574732,0.0001212499,0.00006313018,0.0002145046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2659685,"threshold_uncertainty_score":0.9999354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008957079695054318,"score_gpt":0.254864494822347,"score_spread":0.2459074151272926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}