{"id":"W2046938414","doi":"10.1016/j.neuroscience.2009.10.028","title":"Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system","year":2009,"lang":"en","type":"review","venue":"Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":156,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Eye Institute; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Air Force Office of Scientific Research; Canadian Institutes of Health Research; Human Frontier Science Program; National Institutes of Health; Novo Nordisk Fonden; Medical Research Council Canada","keywords":"Myelin; Syncytium; Neuroscience; Astrocyte; Axon; Oligodendrocyte; Biophysics; Spinal cord; Chemistry; Biology; Cell biology; Action potential; Central nervous system; Electrophysiology; Biochemistry; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002960245,0.0004857754,0.0008329561,0.000214466,0.0008867916,0.0001445446,0.001756075,0.0001163411,0.000002996208],"category_scores_gemma":[0.002506162,0.0002978526,0.0003151733,0.001909042,0.002574414,0.0002163702,0.001114114,0.0007554648,0.000001684827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005773468,"about_ca_system_score_gemma":0.0005515835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001570138,"about_ca_topic_score_gemma":0.000001183388,"domain_scores_codex":[0.9945527,0.001300608,0.0007985654,0.001377831,0.001140512,0.0008297243],"domain_scores_gemma":[0.9974954,0.0006862311,0.0006128076,0.0007432163,0.00009164165,0.0003706935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003185166,0.0002137232,0.001042321,0.004022195,0.000005532832,0.0002172359,0.0002461736,0.0003279564,0.9475809,0.001459867,0.000058006,0.04479427],"study_design_scores_gemma":[0.003575118,0.004875299,0.1212033,0.03847736,0.003819572,0.02529045,0.0005793621,0.01362181,0.3825975,0.0001819337,0.3992479,0.006530436],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7808412,0.2068361,0.00004490793,0.001228137,0.005354269,0.004509751,0.000790015,0.0001690571,0.0002265143],"genre_scores_gemma":[0.8845636,0.1130309,0.00001862416,0.001926567,0.000164315,0.00009857473,1.937997e-7,0.00006893893,0.0001282851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5649834,"threshold_uncertainty_score":0.9999474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05763844586399323,"score_gpt":0.3449378108222501,"score_spread":0.2872993649582569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}