{"id":"W2046938414","doi":"10.1016/j.neuroscience.2009.10.028","title":"Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system","year":2009,"lang":"en","type":"review","venue":"Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":156,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Eye Institute; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Heart, Lung, and Blood Institute; Air Force Office of Scientific Research; Canadian Institutes of Health Research; Human Frontier Science Program; National Institutes of Health; Novo Nordisk Fonden; Medical Research Council Canada","keywords":"Myelin; Syncytium; Neuroscience; Astrocyte; Axon; Oligodendrocyte; Biophysics; Spinal cord; Chemistry; Biology; Cell biology; Action potential; Central nervous system; Electrophysiology; Biochemistry; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000373119,0.0009418376,0.001497025,0.001307009,0.0002115626,0.0007524754,0.00120689,0.0009285468,0.001843092],"category_scores_gemma":[0.0003409107,0.0002381329,0.0003150964,0.001235287,0.0006001607,0.0009870525,0.0004586698,0.001228233,0.002260111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005874366,"about_ca_system_score_gemma":0.0007475947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009092189,"about_ca_topic_score_gemma":0.002131392,"domain_scores_codex":[0.9998908,0.000009961582,0.00001759363,0.0000232939,0.00004472743,0.00001357646],"domain_scores_gemma":[0.9998457,0.00005521398,0.00003428883,0.000006778141,0.00003866006,0.00001933552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001734143,0.00009542613,0.0001906924,0.008630407,0.0001066045,0.0008967953,0.00004293807,0.0004230279,0.01604176,0.004598752,0.0309498,0.9378504],"study_design_scores_gemma":[0.00004441908,0.00008866055,0.001575209,0.001051868,0.000142304,0.003282567,0.00005558505,0.00009460891,0.003563694,0.002736985,0.9873375,0.00002667549],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003639617,0.9970927,0.0004107549,0.0002433897,0.0002742568,0.000008040878,0.00002548569,0.00001540941,0.001565914],"genre_scores_gemma":[0.001203182,0.9971291,0.0003582213,0.0001467625,0.0001243263,0.000007251718,0.00004361712,0.000001883607,0.0009855516],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001843092,"threshold_uncertainty_score":0.006165743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05763844586399323,"score_gpt":0.3449378108222501,"score_spread":0.2872993649582569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}