{"id":"W2046958302","doi":"10.4161/epi.28864","title":"SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells","year":2014,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Wellcome Trust","keywords":"Biology; Cancer research; Nuclear receptor; Estrogen receptor; Nuclear receptor co-repressor 1; Cell biology; Transcription factor; Molecular biology; Genetics; Gene; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009174176,0.0002679757,0.0002008452,0.0003107491,0.0002205597,0.0002925955,0.0002456836,0.0001794614,0.001801541],"category_scores_gemma":[0.0001257206,0.0001489749,0.0002776956,0.0002424339,0.0002156141,0.0001137213,0.0002978744,0.0003334825,0.0005535792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004325535,"about_ca_system_score_gemma":0.0001508683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004825408,"about_ca_topic_score_gemma":0.00109538,"domain_scores_codex":[0.9998446,0.00002391753,0.0000159534,0.00003527878,0.00005474757,0.00002555629],"domain_scores_gemma":[0.9999075,0.00001241699,0.00002317839,0.00001445561,0.00001251808,0.00002998555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001250044,0.00001841108,0.0006651663,0.00003484969,0.000006750235,0.00005588742,0.00001380544,0.00006257411,0.9969141,0.0001128603,0.00006349674,0.001926937],"study_design_scores_gemma":[0.00001234709,0.00008613076,0.01265041,0.000004857627,0.00001358714,0.0003410019,0.0000264211,0.001105687,0.9801272,0.00005892858,0.005568038,0.000005366411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842147,0.005171602,0.004476018,0.000156945,0.00009363914,0.00003039368,0.001666391,0.0001966736,0.00399362],"genre_scores_gemma":[0.9918954,0.001088927,0.001504338,0.00004700679,0.000007931972,0.00001903627,0.001411156,0.00002101624,0.004005271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001801541,"threshold_uncertainty_score":0.006026804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006420452925659575,"score_gpt":0.2242994037211659,"score_spread":0.2178789507955063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}