{"id":"W2046961604","doi":"10.1021/bi049414l","title":"Antimicrobial 14-Helical β-Peptides:  Potent Bilayer Disrupting Agents","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"National Institute of General Medical Sciences","keywords":"Magainin; Antimicrobial peptides; Peptide; Chemistry; Liposome; Membrane; Lipid bilayer; Amphiphile; Bilayer; Biochemistry; Stereochemistry; Biophysics; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001697788,0.000321017,0.0002361626,0.0001362621,0.00008682981,0.0001587612,0.0001302795,0.000211905,0.0005978053],"category_scores_gemma":[0.0001611008,0.0001292205,0.0001153209,0.00008255335,0.000115723,0.0001835611,0.0001588566,0.0002820833,0.0002654982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000767247,"about_ca_system_score_gemma":0.00008523151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006494865,"about_ca_topic_score_gemma":0.00008826175,"domain_scores_codex":[0.999912,0.0000232201,0.000008614055,0.00001094132,0.0000258495,0.00001937966],"domain_scores_gemma":[0.9998832,0.00002663852,0.00002789596,0.000006215236,0.00002019289,0.00003594817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000106689,0.00003058144,0.0002144559,0.00004896954,0.000005236185,0.00004717661,0.000008799134,0.0001079468,0.995874,0.00005246105,0.00001964792,0.003484089],"study_design_scores_gemma":[0.0000335348,0.0009623228,0.001797657,0.000009631752,0.00001554117,0.0004409805,0.0000104921,0.0003329378,0.993108,0.00004573812,0.003239781,0.000003378252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877573,0.007294828,0.002948638,0.00005930373,0.00002766224,0.00006202821,0.0001200237,0.00003744076,0.001692786],"genre_scores_gemma":[0.9903468,0.003226781,0.004685632,0.0001131121,0.00002392086,0.00004327709,0.0002191032,0.00001030166,0.001330991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005978053,"threshold_uncertainty_score":0.001999855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388105798321803,"score_gpt":0.2433335765073663,"score_spread":0.2294525185241483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}