{"id":"W2046970848","doi":"10.1128/jvi.78.19.10636-10649.2004","title":"Activation of TBK1 and IKKε Kinases by Vesicular Stomatitis Virus Infection and the Role of Viral Ribonucleoprotein in the Development of Interferon Antiviral Immunity","year":2004,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Biology; TANK-binding kinase 1; Vesicular stomatitis virus; Kinase; Viral replication; Cell biology; Interferon; Signal transduction; IκB kinase; Virology; Virus; Protein kinase A; Cyclin-dependent kinase 2; NF-κB","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001572195,0.0003652707,0.0001805206,0.0002100867,0.0002016592,0.0003881562,0.000154555,0.0003133812,0.0005900714],"category_scores_gemma":[0.00008853276,0.0001659894,0.0003794291,0.0001075523,0.0002694966,0.0003032,0.0002180836,0.0003889468,0.0002440033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004481317,"about_ca_system_score_gemma":0.000211655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004585253,"about_ca_topic_score_gemma":0.0004863456,"domain_scores_codex":[0.9998553,0.00002748246,0.00001595397,0.00002779655,0.00002580244,0.00004767792],"domain_scores_gemma":[0.9999468,0.000009350552,0.00001821038,0.00000748975,0.000005575111,0.00001246415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001157577,0.00001320832,0.0007241954,0.0000548621,0.0000046985,0.00009235489,0.00001772877,0.00007191426,0.9977875,0.0002135249,0.00001274685,0.0008914716],"study_design_scores_gemma":[0.00001717214,0.0001764643,0.02609681,0.00001336108,0.00002332844,0.0008833676,0.00009279817,0.00130479,0.9687871,0.0002891817,0.002306049,0.000009578778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833215,0.01290258,0.002113181,0.0001129762,0.0000283526,0.00001526341,0.00016903,0.00002307075,0.001314018],"genre_scores_gemma":[0.9953458,0.002512287,0.000872538,0.00002429175,0.00001029057,0.00001762679,0.0002262131,0.000004291701,0.0009866084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005900714,"threshold_uncertainty_score":0.003251493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004897604839283256,"score_gpt":0.2213204072434112,"score_spread":0.216422802404128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}