{"id":"W2047025080","doi":"10.1016/j.bbmt.2008.10.018","title":"Pharmacokinetics and Pharmacodynamics of Plerixafor in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma","year":2009,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Occupational Cancer Research Centre","funders":"","keywords":"Plerixafor; Medicine; Pharmacodynamics; Granulocyte colony-stimulating factor; CXCR4 antagonist; Multiple myeloma; Pharmacokinetics; Lymphoma; Internal medicine; Oncology; Pharmacology; Chemotherapy; CXCR4","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005093922,0.0002903955,0.0007064198,0.0001625832,0.0002226808,0.000376904,0.0001926457,0.0003246951,0.0006130966],"category_scores_gemma":[0.001275085,0.0002194523,0.0003237968,0.0002490605,0.0003484536,0.0003394375,0.0001502917,0.0006215,0.0001461063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007720429,"about_ca_system_score_gemma":0.0005409314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001654576,"about_ca_topic_score_gemma":0.002973484,"domain_scores_codex":[0.9997095,0.0001355416,0.0000144817,0.00003376911,0.00006601679,0.00004056512],"domain_scores_gemma":[0.9994449,0.0001544838,0.0002106808,0.00002406451,0.00002545527,0.000140377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.141143,0.006226314,0.5509214,0.0004653324,0.001176006,0.001348194,0.0007369221,0.00437636,0.06669599,0.0002532319,0.002463605,0.2241935],"study_design_scores_gemma":[0.01226287,0.104407,0.8644045,0.00003119123,0.0005634211,0.003246135,0.0001759085,0.003630032,0.006684404,0.0002131176,0.004350662,0.00003074891],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971234,0.001934232,0.0001825558,0.00006692147,0.000005187281,0.00005680586,0.00006575151,0.00002378854,0.0005413438],"genre_scores_gemma":[0.9988925,0.000375013,0.0002061467,0.0001088967,0.00002180692,0.00004211584,0.0001327457,0.000003079088,0.0002178446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001654576,"threshold_uncertainty_score":0.005601585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006926854741713075,"score_gpt":0.258296062833469,"score_spread":0.2513692080917559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}