{"id":"W2047033006","doi":"10.1016/j.febslet.2004.07.092","title":"ALS2CL, the novel protein highly homologous to the carboxy‐terminal half of ALS2, binds to Rab5 and modulates endosome dynamics","year":2004,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Endosome; Guanine nucleotide exchange factor; Colocalization; Cell biology; Gene product; Biology; GTPase; Gene; Chemistry; Molecular biology; Gene expression; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000133609,0.0001483897,0.0001300569,0.00004012554,0.00009114583,0.00002200551,0.0002354494,0.00008224426,0.000002660134],"category_scores_gemma":[0.00001591344,0.00009777297,0.0000712589,0.0001013313,0.0001014829,0.000003357123,0.00006347727,0.00009031682,0.000003333759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000020199,"about_ca_system_score_gemma":0.00002511817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004437261,"about_ca_topic_score_gemma":0.000462524,"domain_scores_codex":[0.9991871,0.00002237238,0.0001761611,0.0002635656,0.0001305716,0.000220252],"domain_scores_gemma":[0.9994994,0.000006610718,0.00005215848,0.000344215,0.00003187435,0.00006575486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006965961,0.0000272778,0.0003290829,0.00001264192,0.00003238065,0.000009058711,0.000262549,0.00141798,0.9972329,0.000197263,0.00004064206,0.0003685745],"study_design_scores_gemma":[0.001315885,0.000717114,0.01569229,0.00006590892,0.00007806715,0.0001075593,0.0001743678,0.0002920488,0.9567513,0.00008454093,0.02426719,0.0004537391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9596859,0.0001301844,0.0181964,0.02132552,0.00009664784,0.0004860112,0.00004003205,0.000007762053,0.00003149302],"genre_scores_gemma":[0.9963217,0.00001063887,0.000639854,0.002442137,0.0001484358,0.00004946221,0.000269323,0.00001863932,0.00009977169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0404816,"threshold_uncertainty_score":0.3987066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005497282982496781,"score_gpt":0.1962257033291593,"score_spread":0.1907284203466626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}