{"id":"W2047124972","doi":"10.1089/aid.2009.0227","title":"Pharmacokinetic Assessment of Dapivirine Vaginal Microbicide Gel in Healthy, HIV-Negative Women","year":2010,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"U.S. Food and Drug Administration","keywords":"Pharmacokinetics; Microbicide; Vaginal microbicide; Medicine; Internal medicine; Microbicides for sexually transmitted diseases; Human immunodeficiency virus (HIV); Population; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004500853,0.0002600786,0.0003872455,0.0001086134,0.0001275255,0.0002251238,0.0001707918,0.0003540298,0.001110393],"category_scores_gemma":[0.001264453,0.0002127364,0.0001046818,0.00009649673,0.0002028339,0.0002051717,0.0001050909,0.0002573583,0.0001577606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779759,"about_ca_system_score_gemma":0.0002279705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004660873,"about_ca_topic_score_gemma":0.0005028273,"domain_scores_codex":[0.9998026,0.00008752125,0.00000846673,0.00003936774,0.00004012985,0.00002189948],"domain_scores_gemma":[0.9996412,0.0001609782,0.0001096509,0.00001403216,0.00003030759,0.00004394074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1072613,0.005310093,0.1806122,0.001334873,0.0003126758,0.0008341797,0.0009117333,0.00168592,0.4735867,0.0001152777,0.0009260839,0.2271089],"study_design_scores_gemma":[0.008471215,0.4095866,0.4997274,0.0001078663,0.0003716373,0.003536607,0.0006379603,0.004075561,0.06680108,0.0001709613,0.006461915,0.00005118171],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978078,0.001535857,0.0002520584,0.00003840081,0.000007313436,0.00007630848,0.00006191818,0.00001042801,0.0002099569],"genre_scores_gemma":[0.9979442,0.0007001113,0.00069493,0.00008633405,0.00002013056,0.00009884023,0.00008821164,0.000003138881,0.000364159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001110393,"threshold_uncertainty_score":0.003714681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05232004416789409,"score_gpt":0.4257223058859766,"score_spread":0.3734022617180825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}