{"id":"W2047152078","doi":"10.1074/jbc.m608204200","title":"Fibrillin-1 Interactions with Fibulins Depend on the First Hybrid Domain and Provide an Adaptor Function to Tropoelastin","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Deutscher Akademischer Austauschdienst; National Marfan Foundation","keywords":"Tropoelastin; Signal transducing adaptor protein; Function (biology); Domain (mathematical analysis); Fibrillin; Biology; Cell biology; Elastin; Genetics; Mathematics; Signal transduction; Mathematical analysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004104397,0.0001286093,0.0001329183,0.0000249329,0.0001216018,0.0000294889,0.0001632164,0.00007630515,0.00006673113],"category_scores_gemma":[0.0003896113,0.0000718681,0.00005797362,0.00007185709,0.00009131404,0.000006106614,0.0000639329,0.000256272,0.000002538303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003129069,"about_ca_system_score_gemma":0.00004135367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003718063,"about_ca_topic_score_gemma":0.00004831023,"domain_scores_codex":[0.9991668,0.00003760882,0.0002173721,0.0002225918,0.0001510823,0.00020451],"domain_scores_gemma":[0.999262,0.0001241996,0.0001231754,0.0001665355,0.0001589245,0.0001651454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003072792,0.0001313608,0.002876461,0.000009497898,0.00006142379,0.00002763324,0.00002389718,0.00004047931,0.9903486,0.00001390862,0.0009282497,0.002465673],"study_design_scores_gemma":[0.0006688595,0.00422658,0.01327618,0.0000450999,0.00001459069,0.0004326744,0.0007280206,0.00001426006,0.8829204,0.0001133232,0.09736819,0.0001918648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939544,0.0001264098,0.004034837,0.001272189,0.00003115132,0.0001262331,0.00001254356,0.000004441646,0.0004378604],"genre_scores_gemma":[0.9988273,0.00002843625,0.0003886879,0.0002409348,0.0003769512,0.000005117904,0.00001295452,0.000009583172,0.0001100104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1074283,"threshold_uncertainty_score":0.2930696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0233331714916297,"score_gpt":0.2832554470070059,"score_spread":0.2599222755153762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}