{"id":"W2047186390","doi":"10.1002/jcp.10399","title":"Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl‐2 homologs by Fak, PI3‐K/Akt‐1, MEK/Erk, and p38 signaling pathways","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Anoikis; Protein kinase B; Cell biology; MAPK/ERK pathway; Focal adhesion; Integrin; Kinase; Integrin-linked kinase; Biology; Signal transduction; PI3K/AKT/mTOR pathway; Cancer research; Protein kinase A; Programmed cell death; Apoptosis; Cell; Biochemistry; Cyclin-dependent kinase 2","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065145,0.0002162298,0.0001267136,0.0001181997,0.0001390586,0.0002092782,0.00007906766,0.0001294285,0.0009182894],"category_scores_gemma":[0.00006697954,0.0000818034,0.0001335137,0.00009802123,0.0001040226,0.0001553443,0.0001180658,0.0003098344,0.0001752302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001624956,"about_ca_system_score_gemma":0.0001076998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003373938,"about_ca_topic_score_gemma":0.0004572183,"domain_scores_codex":[0.9999081,0.00001608356,0.000006934668,0.00001316722,0.0000236619,0.00003197043],"domain_scores_gemma":[0.9999613,0.000006775635,0.000009081659,0.000004692678,0.000005531014,0.00001268055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002654869,0.00004306947,0.0005417429,0.00004197751,0.000006252647,0.0000656468,0.00001618007,0.00003234996,0.997596,0.00004178833,0.00002367803,0.001325761],"study_design_scores_gemma":[0.00007074271,0.0006921592,0.0326098,0.000008624186,0.00003501604,0.0006911836,0.00008028256,0.001100268,0.9629042,0.00005532995,0.001747457,0.000005096055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971621,0.001743774,0.0005121476,0.00003910099,0.00000617305,0.00001127779,0.0001080989,0.00001104338,0.0004063401],"genre_scores_gemma":[0.9976355,0.0008718853,0.0004890306,0.00002620903,0.00000437405,0.00002412296,0.0002417767,0.000001665521,0.000705488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009182894,"threshold_uncertainty_score":0.003072023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04984311065340385,"score_gpt":0.2936342085619603,"score_spread":0.2437910979085565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}