{"id":"W2047186390","doi":"10.1002/jcp.10399","title":"Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl‐2 homologs by Fak, PI3‐K/Akt‐1, MEK/Erk, and p38 signaling pathways","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Anoikis; Protein kinase B; Cell biology; MAPK/ERK pathway; Focal adhesion; Integrin; Kinase; Integrin-linked kinase; Biology; Signal transduction; PI3K/AKT/mTOR pathway; Cancer research; Protein kinase A; Programmed cell death; Apoptosis; Cell; Biochemistry; Cyclin-dependent kinase 2","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007658534,0.0002281818,0.0007655603,0.0002594061,0.0001632431,0.00001582362,0.0001513817,0.0001546234,0.0002766281],"category_scores_gemma":[0.0002984557,0.0001920457,0.0001604593,0.0001618205,0.0003225894,0.00006718352,0.00008962657,0.0006671535,0.000005084094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004510034,"about_ca_system_score_gemma":0.0001411594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002959957,"about_ca_topic_score_gemma":0.000001725721,"domain_scores_codex":[0.9976186,0.000595627,0.000755688,0.0002767253,0.0003936858,0.0003597341],"domain_scores_gemma":[0.9981852,0.0003763261,0.00047443,0.000230847,0.0004424561,0.0002907788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001608715,0.000345161,0.001967444,0.0001388165,0.00006974804,0.0001087077,0.0001698312,0.00006648126,0.9956541,0.0008307847,0.0002729679,0.0002150563],"study_design_scores_gemma":[0.0048807,0.003559134,0.02877459,0.0001342916,0.000218953,0.000671422,0.0005266607,0.0008758847,0.9521679,0.006497878,0.001380513,0.0003121213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939362,0.00128739,0.003625655,0.00009130687,0.00008012,0.000190611,0.00001548515,0.000008359945,0.0007648617],"genre_scores_gemma":[0.9960587,0.00009669783,0.003414645,0.00005420266,0.0001297077,0.000002161006,0.00002333401,0.00003234469,0.000188188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04348628,"threshold_uncertainty_score":0.7831397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04984311065340385,"score_gpt":0.2936342085619603,"score_spread":0.2437910979085565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}