{"id":"W2047196168","doi":"10.1021/pr300229m","title":"Occurrence and Detection of Phosphopeptide Isomers in Large-Scale Phosphoproteomics Experiments","year":2012,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Phosphopeptide; Phosphoproteomics; Chemistry; Phosphorylation; Peptide; Proteomics; Phosphoserine; Protein–protein interaction; Biochemistry; Computational biology; Protein phosphorylation; Chromatography; Combinatorial chemistry; Biology; Protein kinase A; Serine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001769486,0.001196116,0.0008527543,0.002485022,0.0006708244,0.001445288,0.0009287834,0.001063463,0.0009426451],"category_scores_gemma":[0.002315307,0.0004704861,0.0007930578,0.001513038,0.0005519142,0.001176714,0.0009001834,0.001218159,0.0008798476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000627064,"about_ca_system_score_gemma":0.000734703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007569066,"about_ca_topic_score_gemma":0.0012437,"domain_scores_codex":[0.9983271,0.0001845966,0.0001301016,0.0005640353,0.0006328531,0.0001613758],"domain_scores_gemma":[0.9984899,0.000561879,0.00035662,0.0001472231,0.0003069675,0.0001373824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004945947,0.0001248651,0.004640337,0.0002448613,0.00008349248,0.000215383,0.00009390339,0.001002708,0.9622602,0.0003973637,0.0001569043,0.03028538],"study_design_scores_gemma":[0.00003156398,0.0003229197,0.01814022,0.00002979295,0.0001237825,0.001037552,0.00008335614,0.02660491,0.9507378,0.0006445802,0.002173161,0.00007040986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6462454,0.00238249,0.3459538,0.0002180622,0.00007826342,0.0005604632,0.001248587,0.001705608,0.001607391],"genre_scores_gemma":[0.4858693,0.001594023,0.5076644,0.0002743969,0.0000453506,0.0007087633,0.002189727,0.0003047373,0.001349175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002485022,"threshold_uncertainty_score":0.009358048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04397069235820764,"score_gpt":0.3796082480861366,"score_spread":0.335637555727929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}