{"id":"W2047219888","doi":"10.1038/nrd3373","title":"Cell death assays for drug discovery","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Drug Discovery","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":554,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Programmed cell death; Drug discovery; Computational biology; Cause of death; Medicine; Bioinformatics; Biology; Apoptosis; Disease; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001848327,0.00304359,0.003880805,0.005082414,0.0005879718,0.001997902,0.002238775,0.002364699,0.006227997],"category_scores_gemma":[0.001538191,0.0009713863,0.001050179,0.003822226,0.00234007,0.003764455,0.002170784,0.00482406,0.007086535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002019393,"about_ca_system_score_gemma":0.001553229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008978166,"about_ca_topic_score_gemma":0.001962474,"domain_scores_codex":[0.9991725,0.0001413258,0.00009171046,0.00009394934,0.0004265663,0.00007391143],"domain_scores_gemma":[0.9990678,0.0004538686,0.0001028068,0.00006756266,0.000244378,0.0000635572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001592152,0.0001126702,0.00009041054,0.01005944,0.00009199313,0.000200583,0.00003931555,0.0004794445,0.008573869,0.01259477,0.0766909,0.8909074],"study_design_scores_gemma":[0.000052867,0.0001089436,0.0001476017,0.001021605,0.00007747709,0.0005757249,0.00001997095,0.0001726969,0.003110887,0.005415953,0.9892685,0.000027862],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001228419,0.9928988,0.001639424,0.0006713155,0.001075122,0.00002763068,0.00007347041,0.00006773073,0.003423645],"genre_scores_gemma":[0.001287419,0.992607,0.001426812,0.0007231585,0.0005220701,0.00005548348,0.0001237871,0.000009031597,0.003245198],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006227997,"threshold_uncertainty_score":0.02083474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.043820399536659,"score_gpt":0.3593117519142114,"score_spread":0.3154913523775524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}