{"id":"W2047231876","doi":"10.1128/jvi.80.9.4422-4430.2006","title":"Negative Regulation of the Alpha Interferon-Induced Antiviral Response by the Ras/Raf/MEK Pathway","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Biology; Vesicular stomatitis virus; Interferon; Gene knockdown; RNA interference; Viral replication; Cell biology; Small interfering RNA; Virology; Effector; Vaccinia; Transfection; Viral Interference; Cell culture; Signal transduction; Virus; RNA; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004997558,0.0001040533,0.0002784984,0.00009302571,0.0000845151,0.000007636137,0.0001609573,0.00009692724,0.00009893336],"category_scores_gemma":[0.0003924148,0.00005435594,0.0002590939,0.0001671807,0.0001400327,0.00008890323,0.00004542316,0.0004553287,0.000003766619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007611483,"about_ca_system_score_gemma":0.0001512975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005896995,"about_ca_topic_score_gemma":0.00002318463,"domain_scores_codex":[0.998593,0.0004199155,0.0005376001,0.00009384397,0.0002192686,0.0001363451],"domain_scores_gemma":[0.9985282,0.0003090198,0.0006979686,0.0002231141,0.0002125301,0.00002916835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002790979,0.0001579333,0.001754797,0.000003848964,0.00005179574,0.000005164106,0.000253088,0.00003768015,0.9856603,0.0001099286,0.008547571,0.0006269569],"study_design_scores_gemma":[0.001419545,0.001411326,0.1780372,0.0001000183,0.00007500995,0.0003748703,0.0001090138,0.0001579144,0.811887,0.0004863417,0.00589412,0.00004767259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897519,0.00006981066,0.0001847945,0.008446855,0.0006855987,0.0001351393,0.00001234774,0.000004731527,0.000708766],"genre_scores_gemma":[0.9984463,0.00000294674,0.00006323423,0.0005159303,0.0002331022,0.000001473084,0.00000121526,0.00001214123,0.0007236667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1762824,"threshold_uncertainty_score":0.2216571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376352869724354,"score_gpt":0.2650223593863243,"score_spread":0.2512588306890807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}