{"id":"W2047233829","doi":"10.1110/ps.062660907","title":"Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator","year":2006,"lang":"en","type":"article","venue":"Protein Science","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Repressor; Zinc finger; Transcription factor; Regulator; Chemistry; Transcription (linguistics); Chromatin; Cell biology; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002666003,0.00009591284,0.00006883448,0.00001227324,0.0002670797,0.00003653062,0.0007082137,0.00006472242,0.00006936296],"category_scores_gemma":[0.00005494016,0.0000532945,0.00007022063,0.0002086703,0.0008279141,0.00000698851,0.000114589,0.00008862851,0.000001577659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001064681,"about_ca_system_score_gemma":0.0001896068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001323378,"about_ca_topic_score_gemma":0.00009072206,"domain_scores_codex":[0.9989334,0.00006325187,0.0001491559,0.0002804006,0.0003779326,0.0001958065],"domain_scores_gemma":[0.9993739,0.000007977591,0.00008389613,0.0004242953,0.00007763291,0.0000323149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001685462,0.00001172633,0.0009384424,0.00000349433,0.000002821056,1.26778e-7,0.00005426166,0.00001584428,0.9938765,0.004720639,0.0001267779,0.0002325266],"study_design_scores_gemma":[0.0001701619,0.00003380599,0.02405303,0.0000147757,0.00000307493,0.000004013242,0.00003226024,0.00001394172,0.9500728,0.01585122,0.009671878,0.00007901945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967313,0.0004407147,0.0006930738,0.0006474903,0.0001041125,0.0004008686,0.0001799483,0.000005524007,0.0007969479],"genre_scores_gemma":[0.997334,0.000001234691,0.001999139,0.0001452664,0.0002477058,0.00001629442,0.00001361764,0.000006322725,0.0002364268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04380367,"threshold_uncertainty_score":0.3050484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006470136666759551,"score_gpt":0.2066480041929326,"score_spread":0.200177867526173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}