{"id":"W2047233829","doi":"10.1110/ps.062660907","title":"Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator","year":2006,"lang":"en","type":"article","venue":"Protein Science","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Repressor; Zinc finger; Transcription factor; Regulator; Chemistry; Transcription (linguistics); Chromatin; Cell biology; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002142835,0.0003347129,0.0006031124,0.0001748947,0.0004997277,0.0006287933,0.0005929961,0.0005674097,0.002783931],"category_scores_gemma":[0.0003958264,0.0002292714,0.0001742173,0.0003884571,0.0002089805,0.0002923571,0.0002382814,0.001038963,0.0008651831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001437735,"about_ca_system_score_gemma":0.0008811204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006051571,"about_ca_topic_score_gemma":0.006357769,"domain_scores_codex":[0.9998376,0.00002089375,0.000004451303,0.00002244327,0.00008278286,0.00003170332],"domain_scores_gemma":[0.9998925,0.00001897906,0.00001483582,0.000003075186,0.00003263271,0.00003801886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002451939,0.0007907618,0.008123459,0.001628165,0.0003552862,0.003470027,0.0007132715,0.01348457,0.8499125,0.00880966,0.05300133,0.0572589],"study_design_scores_gemma":[0.003440156,0.001258679,0.1137597,0.0004681571,0.0005614594,0.00675584,0.002412881,0.1428686,0.3319676,0.008939426,0.3872353,0.0003321829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9371075,0.02420062,0.006003848,0.003879582,0.0003866969,0.0001368692,0.005712906,0.0007903662,0.02178146],"genre_scores_gemma":[0.9497016,0.007687965,0.008652331,0.0009443533,0.00007191847,0.0001107453,0.01942469,0.0001523856,0.013254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006051571,"threshold_uncertainty_score":0.01203269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006470136666759551,"score_gpt":0.2066480041929326,"score_spread":0.200177867526173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}