{"id":"W2047290907","doi":"10.1016/j.neuropharm.2014.05.038","title":"PDE4D inhibitors: A potential strategy for the treatment of memory impairment?","year":2014,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Memory impairment; Pharmacology; Neuroscience; Medicine; Psychology; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000623813,0.00009638072,0.00009893751,0.00002090604,0.00007682988,0.00000584445,0.00006899254,0.00006364251,0.00003859643],"category_scores_gemma":[0.0000115956,0.0000643527,0.0001070286,0.00003161425,0.00007896928,0.000001773328,0.00001590039,0.00002350549,0.000003403309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008499365,"about_ca_system_score_gemma":0.00002828163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006766767,"about_ca_topic_score_gemma":0.000003845845,"domain_scores_codex":[0.9994122,0.00007994303,0.0001485999,0.0001777957,0.00004777532,0.0001336601],"domain_scores_gemma":[0.999651,0.00004259583,0.00007729915,0.0001403231,0.00005336727,0.00003545173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005279537,0.0002221096,0.00008378481,0.000009114775,0.00006646328,9.483973e-7,0.00002666971,0.002811492,0.97452,0.00002208062,0.004177239,0.01753214],"study_design_scores_gemma":[0.002956356,0.004902396,0.003106034,0.000001281381,0.0001026279,0.00001515952,0.00002570544,0.003077263,0.8071478,0.00002375785,0.1785465,0.00009510937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957926,0.0003407772,0.001700877,0.0003546815,0.001235235,0.0004106998,0.00001143387,0.00001004267,0.0001436197],"genre_scores_gemma":[0.9976255,0.0002744323,0.00003356398,0.0003828881,0.0007196832,0.00007622623,0.00003063047,0.00001271772,0.0008443718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1743693,"threshold_uncertainty_score":0.2624227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01186141799444384,"score_gpt":0.273789656947048,"score_spread":0.2619282389526041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}