{"id":"W2047298772","doi":"10.1523/jneurosci.3996-13.2014","title":"Neuronal Expression of GalNAc Transferase Is Sufficient to Prevent the Age-Related Neurodegenerative Phenotype of Complex Ganglioside-Deficient Mice","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Neurodegeneration; Biology; Ganglioside; Myelin; Phenotype; Axon; Neuron; Cell biology; Central nervous system; Neuroscience; Pathology; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000232078,0.001163456,0.0006665511,0.0008366916,0.0002283446,0.0005607522,0.0007056887,0.0009046608,0.002040228],"category_scores_gemma":[0.0002171051,0.0004796455,0.0005981253,0.000292354,0.0005873794,0.0004247945,0.0004903579,0.00133844,0.001009793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005381718,"about_ca_system_score_gemma":0.0005039577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001270269,"about_ca_topic_score_gemma":0.001729712,"domain_scores_codex":[0.9996424,0.00002630419,0.00005879575,0.0000992744,0.00008814074,0.00008506262],"domain_scores_gemma":[0.9993995,0.00003861783,0.0002039473,0.00005105601,0.00005780683,0.0002490542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000155386,0.00005583519,0.0001371047,0.00002802238,0.00001366361,0.0000699794,0.00001744796,0.00006459057,0.9987171,0.00009773547,0.00004000558,0.0006031708],"study_design_scores_gemma":[0.0001348142,0.0008836366,0.007272019,0.00003777197,0.00007322434,0.0005686249,0.00006277299,0.001918916,0.9858847,0.0001865967,0.002958743,0.00001814626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918972,0.0009170612,0.00338779,0.0001501783,0.00005643762,0.00007907127,0.001617698,0.0005060281,0.001388663],"genre_scores_gemma":[0.9764202,0.001692092,0.005859487,0.0001535284,0.00003962003,0.000199048,0.003469117,0.0002944301,0.01187249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002040228,"threshold_uncertainty_score":0.006825268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02445554038144615,"score_gpt":0.2893975523562577,"score_spread":0.2649420119748116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}