{"id":"W2047343684","doi":"10.1016/j.ygyno.2005.01.039","title":"Intra-abdominal carcinomatosis after prophylactic oophorectomy in women of hereditary breast ovarian cancer syndrome kindreds associated with BRCA1 and BRCA2 mutations","year":2005,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":false,"ca_institutions":"Coalition for Research in Women's Health","funders":"National Cancer Institute; National Institutes of Health; Nebraska Department of Health and Human Services; Creighton University","keywords":"Medicine; Ovarian cancer; Prophylactic Surgery; Oophorectomy; Lynch syndrome; Disease; Cancer; Genetic testing; Gynecology; Cancer syndrome; Breast cancer; Oncology; Hysterectomy; Internal medicine; Surgery; Colorectal cancer; Germline mutation; Mutation; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002050204,0.0003900922,0.0004162653,0.001048733,0.000791588,0.0004044876,0.0003990886,0.0007440701,0.001832476],"category_scores_gemma":[0.002537577,0.0003347643,0.0005826686,0.0005675774,0.0006672487,0.0003930394,0.0005010761,0.0007846005,0.0002351784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004474877,"about_ca_system_score_gemma":0.0005046194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003065491,"about_ca_topic_score_gemma":0.003825808,"domain_scores_codex":[0.9998105,0.00003347451,0.00001829796,0.00003156363,0.00002846026,0.00007761501],"domain_scores_gemma":[0.9986217,0.0003902782,0.0004183711,0.0001005322,0.00005215526,0.0004170736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004643394,0.0001884513,0.8843037,0.00005097211,0.00009478031,0.1008514,0.0003703838,0.000162871,0.003881082,0.00007832149,0.0003189539,0.005055666],"study_design_scores_gemma":[0.00008978221,0.0008997326,0.8844678,0.00001501492,0.0001110569,0.112538,0.0004538217,0.0002076519,0.0007249698,0.00009664761,0.0003767162,0.00001880267],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984636,0.0003690806,0.00006145133,0.0001091335,0.00002202287,0.000008750524,0.00008527192,0.000006554959,0.0008740729],"genre_scores_gemma":[0.9993549,0.0001975089,0.00003601923,0.0000404579,0.00003740428,0.00000396349,0.00008979061,0.000003357405,0.000236639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003065491,"threshold_uncertainty_score":0.006130278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006936096163197354,"score_gpt":0.246578458902339,"score_spread":0.2396423627391416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}