{"id":"W2047368369","doi":"10.1038/sj.cgt.7700498","title":"Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor","year":2002,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"CD86; Dendritic cell; CD40; CTL*; Biology; Cytotoxic T cell; Immune system; Tumor necrosis factor alpha; Antigen; Molecular biology; Immunology; T cell; In vitro; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000149045,0.0004434962,0.000640172,0.00014875,0.0004076778,0.00004610453,0.0003351951,0.0001602487,0.002278665],"category_scores_gemma":[0.000004341914,0.0003787437,0.0001350181,0.000262954,0.0006163565,0.0002490768,0.0000278112,0.0003436112,0.00003711378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008601748,"about_ca_system_score_gemma":0.00005797633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005325678,"about_ca_topic_score_gemma":0.00003239451,"domain_scores_codex":[0.9979712,0.0003924408,0.0004899346,0.0004922234,0.00008836205,0.0005658595],"domain_scores_gemma":[0.9988779,0.0001355059,0.0002665837,0.0005366178,0.0001417137,0.00004169407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001848514,0.0002908743,0.0002820557,0.00003150664,0.0003879198,0.000003022883,0.001867281,0.00002099854,0.9686424,0.000009311543,0.0003732359,0.02624284],"study_design_scores_gemma":[0.004615459,0.0007977471,0.0007067472,0.00007517038,0.00003048378,0.00005727547,0.0003035013,0.000004859875,0.9793971,0.000005146965,0.0135596,0.000446936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8303376,0.1679063,0.0003373389,0.00008868541,0.0005928545,0.0004361202,0.0001836672,0.00007611705,0.00004120022],"genre_scores_gemma":[0.8897662,0.1070673,0.00009172039,0.0001895637,0.00004564013,0.00009434194,0.00003200213,0.00006922145,0.002644003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.060839,"threshold_uncertainty_score":0.9998664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02181229913662802,"score_gpt":0.2439320365091429,"score_spread":0.2221197373725149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}