{"id":"W2047371312","doi":"10.1021/bi0500224","title":"The Tryptophan-Rich Region of HIV gp41 and the Promotion of Cholesterol-Rich Domains","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Gp41; Amide; Peptide; Chemistry; Tryptophan; Circular dichroism; Biochemistry; Cholesterol; Peptide sequence; Stereochemistry; Amino acid; Biology; Genetics; Antibody; Epitope; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001276795,0.0001364976,0.00008397266,0.00007542271,0.000123215,0.0001603093,0.00008430507,0.0001731737,0.0007275851],"category_scores_gemma":[0.0001192454,0.00007281252,0.0001040995,0.00004995762,0.0001770984,0.0001128985,0.0001562582,0.0001785268,0.0001339267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001356323,"about_ca_system_score_gemma":0.0001448712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00036291,"about_ca_topic_score_gemma":0.0004787098,"domain_scores_codex":[0.9999272,0.00001834452,0.000003405441,0.000007908342,0.00001768784,0.00002547768],"domain_scores_gemma":[0.9999368,0.00001910353,0.00001393984,0.00000648343,0.000006697796,0.00001695937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007682516,0.0000110466,0.000144835,0.00001229463,0.000001280663,0.00004779285,0.000008453795,0.0000292935,0.9987798,0.0001168553,0.000008378788,0.0007630568],"study_design_scores_gemma":[0.00001723028,0.0002347061,0.005040003,0.00000394362,0.000004620864,0.0003599701,0.00002138815,0.0003242115,0.9927249,0.00008875614,0.0011774,0.000002884268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981716,0.000717383,0.0002950084,0.00002772901,0.00000343186,0.000005586734,0.00001646051,0.00000426799,0.0007584713],"genre_scores_gemma":[0.9987376,0.0002366753,0.0003984941,0.00002010937,0.000003096254,0.000004844522,0.00003453467,0.000002104614,0.000562512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007275851,"threshold_uncertainty_score":0.002434015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051107950934138,"score_gpt":0.2437329698785148,"score_spread":0.2332218903691735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}