{"id":"W2047371312","doi":"10.1021/bi0500224","title":"The Tryptophan-Rich Region of HIV gp41 and the Promotion of Cholesterol-Rich Domains","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Gp41; Amide; Peptide; Chemistry; Tryptophan; Circular dichroism; Biochemistry; Cholesterol; Peptide sequence; Stereochemistry; Amino acid; Biology; Genetics; Antibody; Epitope; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001751748,0.00007780539,0.0001211806,0.00001185484,0.0001249763,0.000006345151,0.0001386721,0.0001020917,0.00002285526],"category_scores_gemma":[0.00006383235,0.0000399367,0.00004023424,0.00005743913,0.0005610304,0.00001770792,0.00005237989,0.0001057879,0.0000259301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001799752,"about_ca_system_score_gemma":0.00003432969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007003447,"about_ca_topic_score_gemma":0.000004261468,"domain_scores_codex":[0.9994412,0.00008057825,0.0001613847,0.0001224908,0.00003815417,0.0001562035],"domain_scores_gemma":[0.9994688,0.0001179778,0.00009393987,0.000258232,0.00004739933,0.00001364607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004770239,0.000336934,0.004841747,0.00007537969,0.0002732592,0.00000181892,0.0005012671,5.395103e-7,0.9702235,0.0002983527,0.006884913,0.01608521],"study_design_scores_gemma":[0.002635065,0.00007265872,0.004562956,0.00002313314,0.00002557861,0.00004750774,0.0001590397,0.000001799044,0.9882587,0.00005363358,0.004115554,0.0000443821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927664,0.003996855,0.00001566198,0.001836043,0.00002486353,0.0001600885,0.00002308019,0.000007870375,0.001169097],"genre_scores_gemma":[0.9958727,0.0003819265,0.00001775521,0.00001127061,0.00002648742,0.00002440317,0.00004613211,0.000004262823,0.00361503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01803514,"threshold_uncertainty_score":0.206714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051107950934138,"score_gpt":0.2437329698785148,"score_spread":0.2332218903691735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}