{"id":"W2047392405","doi":"10.1016/j.exer.2010.05.016","title":"Neurotrophic factor delivery as a protective treatment for glaucoma","year":2010,"lang":"en","type":"review","venue":"Experimental Eye Research","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Eye Institute; Fight for Sight UK; National Institutes of Health; University Hospitals Bristol NHS Foundation Trust; Jukes Glaucoma Research Fund; McGill University; GlaxoSmithKline","keywords":"Neuroprotection; Neurotrophic factors; Ciliary neurotrophic factor; Medicine; Glaucoma; Glial cell line-derived neurotrophic factor; Retinal ganglion cell; Neuroscience; Neurotrophin; Nerve growth factor; Optic nerve; Ophthalmology; Pharmacology; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006506702,0.001268766,0.001792525,0.001686365,0.0002867412,0.0008163797,0.001160505,0.001362994,0.002229818],"category_scores_gemma":[0.000505319,0.0002951602,0.0004945563,0.001530635,0.0006796495,0.001077707,0.0004760476,0.002411335,0.001610017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007933605,"about_ca_system_score_gemma":0.0008228386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001426582,"about_ca_topic_score_gemma":0.002882616,"domain_scores_codex":[0.9998547,0.00001757448,0.00002426014,0.00002826881,0.00005864806,0.00001648465],"domain_scores_gemma":[0.9998111,0.00009232729,0.00002594515,0.000008268823,0.00004445143,0.00001787734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002803725,0.0001784952,0.00009859286,0.009108924,0.0001248212,0.0004260965,0.00003660426,0.0003820761,0.007623925,0.003471606,0.03435924,0.9439091],"study_design_scores_gemma":[0.000177254,0.0002638559,0.0007737713,0.002215386,0.0003381195,0.002679922,0.00005672194,0.0002518275,0.004765024,0.002822521,0.9856191,0.00003643762],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003201892,0.9975102,0.0004114303,0.0002381051,0.000352891,0.000008519783,0.00002729664,0.00001643812,0.001114796],"genre_scores_gemma":[0.001904176,0.9952743,0.0007627651,0.0002827922,0.0002573114,0.00001834727,0.00006560767,0.000005121402,0.001429427],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002229818,"threshold_uncertainty_score":0.007459462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1174705580693689,"score_gpt":0.4646811584636412,"score_spread":0.3472106003942722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}