{"id":"W2047559912","doi":"10.1074/mcp.m000153-mcp201","title":"Studies of Phosphoproteomic Changes Induced by Nucleophosmin-Anaplastic Lymphoma Kinase (ALK) Highlight Deregulation of Tumor Necrosis Factor (TNF)/Fas/TNF-related Apoptosis-induced Ligand Signaling Pathway in ALK-positive Anaplastic Large Cell Lymphoma","year":2010,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Anaplastic lymphoma kinase; Anaplastic large-cell lymphoma; Cancer research; Tyrosine kinase; Signal transduction; Tumor necrosis factor alpha; Biology; Nucleophosmin; Chemistry; Cell biology; Lymphoma; Immunology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145316,0.0002983268,0.0001963172,0.0006351171,0.0001746737,0.0002240675,0.0001183997,0.0002183184,0.001292496],"category_scores_gemma":[0.0001072013,0.0001172605,0.0002950654,0.000557415,0.0001424836,0.0002063058,0.000184792,0.0002857263,0.0002617986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001722349,"about_ca_system_score_gemma":0.00009088452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000441634,"about_ca_topic_score_gemma":0.0007261971,"domain_scores_codex":[0.9999239,0.000006269509,0.000005491996,0.00002290358,0.00001963347,0.00002176133],"domain_scores_gemma":[0.9999263,0.000009752005,0.00003020505,0.000003362934,0.000009201035,0.00002121155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001711007,0.00001379195,0.001098669,0.00005532576,0.00001681985,0.0000896582,0.00002270895,0.00003343369,0.9974207,0.00003295379,0.00004036208,0.001004527],"study_design_scores_gemma":[0.00002796959,0.0003809387,0.1901961,0.00001720207,0.0001318653,0.001889562,0.0001963951,0.002142023,0.8012906,0.0001798374,0.003526317,0.0000212508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929793,0.00223765,0.002056401,0.00006303104,0.00002587028,0.0000259913,0.001826241,0.00005844765,0.0007270339],"genre_scores_gemma":[0.987964,0.002284143,0.005337328,0.0001007259,0.00001696913,0.00007918044,0.002418436,0.00002422791,0.001774952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001292496,"threshold_uncertainty_score":0.00432384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00991259370227219,"score_gpt":0.2212360942585148,"score_spread":0.2113235005562426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}