{"id":"W2047587652","doi":"10.1002/btpr.1799","title":"Cholic acid modified 2 kDa polyethylenimine as efficient transfection agent","year":2013,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Polyethylenimine; Cholic acid; Transfection; Chemistry; Polymer; Grafting; HEK 293 cells; Gene delivery; Combinatorial chemistry; Biochemistry; Organic chemistry; Gene; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003402786,0.0004692746,0.0003734195,0.0002076026,0.0001165077,0.0003688179,0.0002757267,0.0004656703,0.0004470552],"category_scores_gemma":[0.0002511478,0.0002073804,0.0002599132,0.0002228371,0.0002299972,0.0003741001,0.0002466852,0.0004097206,0.000544461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004529216,"about_ca_system_score_gemma":0.00029274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005833964,"about_ca_topic_score_gemma":0.001013254,"domain_scores_codex":[0.9997786,0.00005043673,0.00002925162,0.00004744884,0.00005903662,0.00003534316],"domain_scores_gemma":[0.9998544,0.0000288365,0.00004172586,0.00001985059,0.00003048982,0.00002460188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001724141,0.00000360894,0.00002570034,0.00001933126,0.000001449121,0.00001922406,0.000005181543,0.00003097671,0.9993581,0.00003460606,0.000006372641,0.0004780952],"study_design_scores_gemma":[0.000004729562,0.0000540209,0.0002365008,0.000002301536,0.000006559581,0.00007064344,0.000002223633,0.0002920403,0.9978117,0.00001072404,0.001505373,0.000003126097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9530858,0.005529372,0.03788782,0.0001593554,0.00009902888,0.0001129226,0.0002313642,0.0003247041,0.002569606],"genre_scores_gemma":[0.96161,0.002425687,0.02663817,0.0001003755,0.00002095094,0.0001111422,0.0004543443,0.00008477271,0.008554452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005833964,"threshold_uncertainty_score":0.003286183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009035575366506138,"score_gpt":0.2422097809087072,"score_spread":0.2331742055422011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}