{"id":"W2047587652","doi":"10.1002/btpr.1799","title":"Cholic acid modified 2 kDa polyethylenimine as efficient transfection agent","year":2013,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Polyethylenimine; Cholic acid; Transfection; Chemistry; Polymer; Grafting; HEK 293 cells; Gene delivery; Combinatorial chemistry; Biochemistry; Organic chemistry; Gene; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006755262,0.0002081565,0.0001597944,0.0001247006,0.00009762574,0.00003230697,0.0003247647,0.0006333454,0.0001024556],"category_scores_gemma":[0.00002243257,0.0001872396,0.0001052928,0.000134189,0.0002709851,0.000004271029,0.0001125543,0.0001732931,0.0002536386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001897275,"about_ca_system_score_gemma":0.00003298882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006720077,"about_ca_topic_score_gemma":0.00001092773,"domain_scores_codex":[0.998799,0.00002673454,0.0002072055,0.0004795466,0.0001098232,0.0003776631],"domain_scores_gemma":[0.9993089,0.000002555263,0.00006190423,0.0004762381,0.0000749032,0.00007545868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005034642,0.0001373827,0.0002099864,0.0000125698,0.00005853839,0.000004981913,0.00002556343,0.00002548665,0.9357495,0.0002013142,0.000490815,0.06303354],"study_design_scores_gemma":[0.0004645383,0.0006579665,0.000780075,0.00001448144,0.00001694183,0.00006011356,0.00006346605,0.0003141236,0.9891512,0.00006294438,0.008185172,0.0002289989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993481,0.002440896,0.001092192,0.001752149,0.000253377,0.0003414481,0.000006761274,0.0001178961,0.0005142894],"genre_scores_gemma":[0.9982595,0.0003829616,0.0002386411,0.0002180224,0.0001164456,0.0002108391,0.00005264787,0.00002291429,0.0004979671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06280454,"threshold_uncertainty_score":0.7635408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009035575366506138,"score_gpt":0.2422097809087072,"score_spread":0.2331742055422011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}