{"id":"W2047589932","doi":"10.1007/s00428-015-1755-2","title":"Familial pheochromocytoma and renal cell carcinoma syndrome: TMEM127 as a novel candidate gene for the association","year":2015,"lang":"en","type":"article","venue":"Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin","topic":"Adrenal and Paraganglionic Tumors","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto; University Health Network","funders":"","keywords":"SDHD; Pheochromocytoma; SDHB; Germline mutation; Paraganglioma; Renal cell carcinoma; Germline; Biology; Cancer research; Mutation; Pathology; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001940002,0.0006151181,0.001063222,0.0002060758,0.000423268,0.00004962183,0.0005084557,0.0003997241,0.00002869434],"category_scores_gemma":[0.002017316,0.0003828575,0.0003151263,0.0004284731,0.0007678654,0.0001382949,0.0003538609,0.001004473,0.00008150974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001802094,"about_ca_system_score_gemma":0.0008782983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005337612,"about_ca_topic_score_gemma":0.00004424085,"domain_scores_codex":[0.9961805,0.0003111357,0.0007869931,0.0009717107,0.0007061538,0.001043455],"domain_scores_gemma":[0.99576,0.002010356,0.0005286096,0.0008168087,0.0002732802,0.0006109829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.04276839,0.008414781,0.07854115,0.002448261,0.008047325,0.03820728,0.0269367,0.002247862,0.6095753,0.02732105,0.1046267,0.05086514],"study_design_scores_gemma":[0.08286166,0.03145777,0.5619193,0.0007401331,0.01040986,0.01370047,0.008694344,0.01962631,0.1879225,0.03507198,0.04300858,0.004587075],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825265,0.005192597,0.003207899,0.002705676,0.0006148382,0.001524378,0.0002467635,0.0001761239,0.003805227],"genre_scores_gemma":[0.9912449,0.0002861143,0.003031771,0.002471356,0.0007918844,0.0001782121,0.0004174506,0.00006822087,0.001510162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4833781,"threshold_uncertainty_score":0.9998623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03620781877671692,"score_gpt":0.3330363007827618,"score_spread":0.2968284820060449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}