{"id":"W2047660235","doi":"10.1016/j.mce.2012.02.006","title":"CYP24 inhibition preserves 1α,25-dihydroxyvitamin D3 anti-proliferative signaling in lung cancer cells","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"Calcitriol receptor; Cyclin; Cancer research; Lung cancer; Growth inhibition; Cyclin D1; Cancer cell; Signal transduction; Cell growth; Biology; Cell cycle; Vitamin D and neurology; Chemistry; Cell biology; Endocrinology; Internal medicine; Cell; Cancer; Biochemistry; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002078716,0.0003125178,0.0005950494,0.0004949424,0.0006238237,0.0007505289,0.0005212697,0.0004684263,0.004986765],"category_scores_gemma":[0.0002640092,0.0002044539,0.000589117,0.0005310448,0.0003738551,0.0003034426,0.0001806767,0.000913754,0.001279426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004425502,"about_ca_system_score_gemma":0.0006140145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002466867,"about_ca_topic_score_gemma":0.003088475,"domain_scores_codex":[0.9997247,0.00004715389,0.00002523037,0.00004942212,0.00006378497,0.00008972033],"domain_scores_gemma":[0.9998214,0.0000368461,0.00001932549,0.00004951315,0.00002858311,0.00004444929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001573792,0.0002464683,0.0004787778,0.0000770552,0.00003279678,0.0002129911,0.00005207177,0.0001507624,0.9879792,0.0001712045,0.001209043,0.007815833],"study_design_scores_gemma":[0.00007310143,0.00064153,0.003325669,0.000003085114,0.00003105078,0.0001904986,0.00007069501,0.0003271028,0.9873784,0.00005563158,0.007894807,0.000008400553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878646,0.003762244,0.000964463,0.0005952836,0.0002675197,0.00005037224,0.001755568,0.000351823,0.004388041],"genre_scores_gemma":[0.9865015,0.001409848,0.0007173293,0.0001181604,0.00004839186,0.00006097083,0.001324625,0.00004582104,0.009773398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004986765,"threshold_uncertainty_score":0.01668239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01519328963419596,"score_gpt":0.2961192870759692,"score_spread":0.2809259974417732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}