{"id":"W2047660235","doi":"10.1016/j.mce.2012.02.006","title":"CYP24 inhibition preserves 1α,25-dihydroxyvitamin D3 anti-proliferative signaling in lung cancer cells","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"Calcitriol receptor; Cyclin; Cancer research; Lung cancer; Growth inhibition; Cyclin D1; Cancer cell; Signal transduction; Cell growth; Biology; Cell cycle; Vitamin D and neurology; Chemistry; Cell biology; Endocrinology; Internal medicine; Cell; Cancer; Biochemistry; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002604045,0.0002690642,0.0004876631,0.0003123565,0.00010785,0.00002449436,0.00009273854,0.0001298961,0.00009000616],"category_scores_gemma":[0.00008738555,0.0002395564,0.00009809614,0.0002531926,0.0002003115,0.0001505099,0.000172024,0.0004545415,0.00001350519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000775725,"about_ca_system_score_gemma":0.00004948461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001484156,"about_ca_topic_score_gemma":0.00001540281,"domain_scores_codex":[0.9976573,0.0003338262,0.000309239,0.0004069305,0.0003385269,0.0009542064],"domain_scores_gemma":[0.9993381,0.0000755613,0.00006357691,0.0002651311,0.00008287369,0.0001747916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002731488,0.0002896099,0.05732505,0.0003574492,0.0001401321,0.001396821,0.001506926,0.00002760682,0.9374471,0.0009425565,0.0002489673,0.000290497],"study_design_scores_gemma":[0.001841547,0.0002191193,0.01881283,0.0001286526,0.0001295714,0.0001276913,0.0007302014,0.0002279124,0.9767723,0.00007533184,0.0006895675,0.0002452645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741386,0.02226634,0.0006554511,0.0008192385,0.0001335081,0.0006731491,0.00001207427,0.00004091675,0.001260765],"genre_scores_gemma":[0.998017,0.0006876928,0.0002719418,0.0003608235,0.0001654567,0.0002109835,0.00004166379,0.00003263513,0.0002118589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03932524,"threshold_uncertainty_score":0.9768826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01519328963419596,"score_gpt":0.2961192870759692,"score_spread":0.2809259974417732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}