{"id":"W2047672544","doi":"10.1074/jbc.m111.261172","title":"Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter jejuni","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; National Research Council Canada; Institute for Biological Sciences; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Canadian Institutes of Health Research; University of British Columbia; Kwanjeong Educational Foundation; Centre for Blood Research, University of British Columbia; Michael Smith Health Research BC; Canadian Light Source; Howard Hughes Medical Institute","keywords":"Sialyltransferase; Campylobacter jejuni; Substrate (aquarium); Chemistry; Substrate specificity; Microbiology; Biochemistry; Biology; Enzyme; Bacteria; Ecology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002125561,0.0004442711,0.0003674095,0.0002556406,0.0002234191,0.0003757639,0.0007252314,0.0003537062,0.001114279],"category_scores_gemma":[0.0004550703,0.0002638605,0.0003827612,0.0004243305,0.0001702523,0.000298202,0.0001373473,0.0008016771,0.0003389932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001335494,"about_ca_system_score_gemma":0.0003613499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008517493,"about_ca_topic_score_gemma":0.004995802,"domain_scores_codex":[0.9997967,0.00001688216,0.00001111903,0.00004256618,0.00007804846,0.00005467826],"domain_scores_gemma":[0.9997573,0.00005357381,0.00004939651,0.00001463268,0.00007242759,0.00005268495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000584822,0.0001710679,0.003267155,0.0001402639,0.00003794791,0.0001967327,0.00009612543,0.004138789,0.9881333,0.0003472561,0.000363176,0.00252338],"study_design_scores_gemma":[0.00004271556,0.0005306532,0.03481963,0.00002025645,0.00005877755,0.0004211482,0.0002314698,0.08429614,0.8766321,0.0001680808,0.002724556,0.00005450747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967986,0.0006578343,0.000930909,0.00008684053,0.00001321737,0.000007971706,0.0004178069,0.00003356134,0.00105346],"genre_scores_gemma":[0.9943331,0.0004170648,0.001467284,0.00003416537,0.000005164884,0.00001076441,0.002390564,0.00002840442,0.001313415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008517493,"threshold_uncertainty_score":0.01693583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03557498054693044,"score_gpt":0.2686965563651022,"score_spread":0.2331215758181718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}