{"id":"W2047703874","doi":"10.1016/j.neuroscience.2009.05.026","title":"The generation of an array of clonal, immortalized cell models from the rat hypothalamus: analysis of melatonin effects on kisspeptin and gonadotropin-inhibitory hormone neurons","year":2009,"lang":"en","type":"article","venue":"Neuroscience","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of New Brunswick; University Health Network; Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Kisspeptin; Cell culture; Melatonin; Endocrinology; Internal medicine; Gonadotropin; Hypothalamus; Gonadotropin-releasing hormone; Hormone; Luteinizing hormone; Neuropeptide; Receptor; Cell biology; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004008405,0.0003943883,0.0003710003,0.0007370141,0.0003440578,0.0005314686,0.0003864705,0.0003086625,0.00119554],"category_scores_gemma":[0.0003251124,0.0002343536,0.000514139,0.0003245011,0.0002671329,0.0003525409,0.0003104977,0.00118767,0.0005926933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002505044,"about_ca_system_score_gemma":0.0003496119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007994979,"about_ca_topic_score_gemma":0.002150241,"domain_scores_codex":[0.9997874,0.00002159628,0.00003627075,0.0000418154,0.00006814205,0.00004475719],"domain_scores_gemma":[0.999689,0.00007548782,0.00005729484,0.00007238839,0.00004812,0.00005769809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006139894,0.0000370047,0.0003125467,0.00001699074,0.000009046038,0.00006091869,0.00003307162,0.0000488083,0.9982814,0.0001533096,0.0000389482,0.0009465681],"study_design_scores_gemma":[0.00001842622,0.0002619789,0.003052857,0.000006319725,0.00007087541,0.0003751406,0.00005664362,0.0007480686,0.992399,0.0000931334,0.002910179,0.000007376306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686158,0.002047488,0.02478088,0.0002150161,0.0001681252,0.0001828293,0.001942883,0.0001528717,0.001894046],"genre_scores_gemma":[0.9542924,0.003553972,0.03041625,0.0001835657,0.00006808815,0.0003639684,0.004499913,0.0001540415,0.006467745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00119554,"threshold_uncertainty_score":0.003999531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02602411984423351,"score_gpt":0.2608110377503685,"score_spread":0.234786917906135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}