{"id":"W2047734512","doi":"10.1021/bi035432b","title":"Metal Ion Binding Properties and Conformational States of Calcium- and Integrin-Binding Protein","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Biophysics; Conformational change; Calcium; Protein structure; Calcium-binding protein; Calmodulin; Binding site; Integrin; Binding domain; EF hand; Protein secondary structure; Biochemistry; Plasma protein binding; Receptor; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002207717,0.0002395635,0.0002061978,0.0002070171,0.0001846706,0.0003248298,0.0003208545,0.0003361013,0.0009567792],"category_scores_gemma":[0.0006359869,0.0001882456,0.0001103815,0.0002176397,0.0003082079,0.0002302747,0.0001290163,0.0003365202,0.0002168157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003346794,"about_ca_system_score_gemma":0.00008373021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130762,"about_ca_topic_score_gemma":0.0005434598,"domain_scores_codex":[0.9998057,0.0000305494,0.000009076611,0.00006010019,0.00004947159,0.00004509392],"domain_scores_gemma":[0.9998025,0.00005688683,0.00005271247,0.00001294988,0.00003063121,0.0000443262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002682586,0.00001897402,0.001355893,0.00002829028,0.00001254214,0.00003519603,0.0000504991,0.0001161602,0.9971303,0.00008276185,0.00004424168,0.0008567196],"study_design_scores_gemma":[0.00005711886,0.0003743391,0.06683047,0.00001117043,0.00002688577,0.0005236318,0.0001083866,0.004886838,0.9248013,0.0002286324,0.002115814,0.00003549548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980832,0.0007530542,0.0006128381,0.0000342451,0.00000516483,0.000004037535,0.00007696086,0.0000108013,0.0004196306],"genre_scores_gemma":[0.9985246,0.0002077063,0.0005146752,0.00003928684,0.000005209444,0.000009054266,0.0002402036,0.000009833019,0.0004493398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001130762,"threshold_uncertainty_score":0.00320071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02234205455282872,"score_gpt":0.2376605425793838,"score_spread":0.2153184880265551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}