{"id":"W2047746661","doi":"10.1038/35107009","title":"Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication","year":2001,"lang":"en","type":"article","venue":"Nature","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":759,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Degron; Phosphorylation; Cyclin-dependent kinase; DNA replication; Origin recognition complex; Cell biology; S phase; Biology; Ubiquitin; Cell division control protein 4; Chemistry; Biochemistry; Ubiquitin ligase; DNA; Cell cycle; Eukaryotic DNA replication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01297838539828327,"score_gpt":0.2795146740371363,"score_spread":0.266536288638853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}