{"id":"W2047749014","doi":"10.1139/o04-045","title":"Gene regulation by Sp1 and Sp3","year":2004,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":418,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Sp1 transcription factor; Gene; Promoter; Transcription (linguistics); Biology; Transcriptional regulation; Regulation of gene expression; Transcription factor; Zinc finger; Genetics; Gene expression; Cell biology; Molecular biology; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009961197,0.0004001661,0.0005668401,0.00002423089,0.00008653053,0.00002773037,0.0001724873,0.001036251,0.00001477465],"category_scores_gemma":[0.00001461209,0.0003640499,0.0001334423,0.00004687775,0.0001963825,0.000001228924,0.0002120895,0.0001556753,0.000004890725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000269973,"about_ca_system_score_gemma":0.000148958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006521726,"about_ca_topic_score_gemma":6.864995e-7,"domain_scores_codex":[0.9986101,0.00004215124,0.0003420711,0.000701857,0.00003884662,0.0002649156],"domain_scores_gemma":[0.9992378,0.00001180236,0.0002362931,0.000365482,0.00002611599,0.0001225063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001565712,0.00007960608,0.00001663742,0.01015669,0.0001553357,0.000003352125,0.000008669354,8.232983e-7,0.5482612,0.00005052159,0.001102751,0.4401488],"study_design_scores_gemma":[0.0002817537,0.0001136892,0.000001260592,0.0002997202,0.0001584339,0.00009899471,0.000006804208,0.000003367762,0.05646319,0.00009906841,0.9420103,0.0004634451],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01262931,0.9858811,0.00006244511,0.00001000892,0.00008443714,0.0001913533,0.0002979717,0.0000100831,0.0008332722],"genre_scores_gemma":[0.004415661,0.9884059,0.0004174022,0.00003083689,0.0002159195,0.0000265165,0.004952756,0.0000390298,0.001495912],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9409075,"threshold_uncertainty_score":0.9998811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006896006508602504,"score_gpt":0.2336785999033351,"score_spread":0.2267825933947326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}