{"id":"W2047757141","doi":"10.1021/bi034086v","title":"Ligand Specificity in the CRAL-TRIO Protein Family","year":2003,"lang":"en","type":"article","venue":"Biochemistry","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Ligand (biochemistry); Chemistry; Computational biology; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958733,0.0004362038,0.0004177245,0.0003318391,0.000345602,0.000588277,0.0004192628,0.0005263351,0.001989079],"category_scores_gemma":[0.0004090392,0.0001870303,0.0003940946,0.0004076916,0.000378715,0.0003638404,0.0004370048,0.0005918522,0.002401916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008948931,"about_ca_system_score_gemma":0.0003708535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001636139,"about_ca_topic_score_gemma":0.00137628,"domain_scores_codex":[0.9996707,0.00004401683,0.00002194098,0.0001148097,0.00008206441,0.00006642598],"domain_scores_gemma":[0.9997078,0.00004438156,0.00007741285,0.0000429941,0.00005245654,0.0000749977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002377019,0.0000254921,0.001288523,0.00009432785,0.00001083159,0.0002620528,0.00004064577,0.0001128598,0.9902998,0.0004914948,0.000327393,0.006808759],"study_design_scores_gemma":[0.00005970126,0.0002899266,0.02817122,0.00003285999,0.00005831934,0.008585135,0.000162275,0.005314607,0.9002209,0.0004051428,0.0566478,0.0000521589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679056,0.01094855,0.01203433,0.0005441823,0.00005968417,0.00006255742,0.000989738,0.0009455547,0.00650971],"genre_scores_gemma":[0.9743937,0.003585004,0.01070279,0.0004919422,0.00003709309,0.00009516629,0.003194782,0.0001357292,0.007363864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001989079,"threshold_uncertainty_score":0.006654084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008854531417941963,"score_gpt":0.228123331415661,"score_spread":0.2192687999977191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}