{"id":"W2047791077","doi":"10.1371/journal.pone.0036704","title":"Multiple Roles of Integrin-Linked Kinase in Epidermal Development, Maturation and Pigmentation Revealed by Molecular Profiling","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University; Lawson Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Integrin-linked kinase; Biology; Hair follicle; Epidermis (zoology); Scaffold protein; Morphogenesis; Kinase; Signal transduction; Genetics; Protein kinase A; Gene; Cyclin-dependent kinase 2","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000881979,0.0001653572,0.0001718945,0.0005306696,0.0001979678,0.0004210703,0.00008409919,0.0001795097,0.0004480902],"category_scores_gemma":[0.0001330197,0.00009543921,0.000166945,0.0003594985,0.0001629449,0.0002440189,0.000154954,0.0002944741,0.0001937733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001899232,"about_ca_system_score_gemma":0.00014235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003110369,"about_ca_topic_score_gemma":0.0006999656,"domain_scores_codex":[0.9998748,0.0000127924,0.000007153654,0.00003901312,0.00003619986,0.00002999484],"domain_scores_gemma":[0.9999175,0.00001421182,0.00003195876,0.000007233974,0.0000122958,0.00001682965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009716284,0.000006919598,0.002107624,0.00002223896,0.000005427956,0.00003057096,0.00001514455,0.00003879701,0.9955546,0.00005039555,0.00001818033,0.002052796],"study_design_scores_gemma":[0.00001332472,0.0002395355,0.3357898,0.00002083686,0.0001103774,0.0007495998,0.0002697599,0.002797185,0.6551881,0.0005263732,0.004271592,0.00002349483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926527,0.002448257,0.002965729,0.00007231645,0.000009491646,0.00001623975,0.0007392472,0.00004107253,0.001054911],"genre_scores_gemma":[0.9913101,0.00202318,0.004077021,0.00006926956,0.000009557853,0.00002819984,0.000914967,0.00001820057,0.001549433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005306696,"threshold_uncertainty_score":0.001498997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04952360998169032,"score_gpt":0.2919492009339117,"score_spread":0.2424255909522214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}